Localization of Enzymes Within the Cell

Related Posts:

Organelles and structural order in metabolism. Organelles such as the mitochondrion (TEM) contain enzymes that carry out specific functions, in this case the second and third stages of cellular respiration.
Source: Urry, Lisa A.. Campbell Biology (p. 161). Pearson Education. Kindle Edition.

Localization of Enzymes Within the Cell (Campbell Biology)

The cell is not just a bag of chemicals with thousands of different kinds of enzymes and substrates in a random mix. The cell is compartmentalized, and cellular structures help bring order to metabolic pathways. In some cases, a team of enzymes for several steps of a metabolic pathway are assembled into a multi-enzyme complex. The arrangement facilitates the sequence of reactions, with the product from the first enzyme becoming the substrate for an adjacent enzyme in the complex, and so on, until the end product is released. Some enzymes and enzyme complexes have fixed locations within the cell and act as structural components of particular membranes. Others are in solution within particular membrane-enclosed eukaryotic organelles, each with its own internal chemical environment. For example, in eukaryotic cells, the enzymes for the second and third stages of cellular respiration reside in specific locations within mitochondria.


Urry, Lisa A.. Campbell Biology. Pearson Education. Kindle Edition. https://www.pearson.com/us/higher-education/series/Campbell-Biology-Series/2244849.html

Related Research

Research Article: Functional Representation of Enzymes by Specific Peptides

Date Published: August 24, 2007 Publisher: Public Library of Science Author(s): Vered Kunik, Yasmine Meroz, Zach Solan, Ben Sandbank, Uri Weingart, Eytan Ruppin, David Horn, Yanay Ofran Abstract: Predicting the function of a protein from its sequence is a long-standing goal of bioinformatic research. While sequence similarity is the most popular tool used for this … Continue reading

Research Article: The dUTPase Enzyme Is Essential in Mycobacterium smegmatis

Date Published: May 24, 2012 Publisher: Public Library of Science Author(s): Ildiko Pecsi, Rita Hirmondo, Amanda C. Brown, Anna Lopata, Tanya Parish, Beata G. Vertessy, Judit Tóth, Olivier Neyrolles. http://doi.org/10.1371/journal.pone.0037461 Abstract: Thymidine biosynthesis is essential in all cells. Inhibitors of the enzymes involved in this pathway (e.g. methotrexate) are thus frequently used as cytostatics. Due to … Continue reading

Research Article: Mapping of Enzyme Kinetics on a Microfluidic Device

Date Published: April 15, 2016 Publisher: Public Library of Science Author(s): Hoon Suk Rho, Alexander Thomas Hanke, Marcel Ottens, Han Gardeniers, David T. Eddington. http://doi.org/10.1371/journal.pone.0153437 Abstract: A microfluidic platform or “microfluidic mapper” is demonstrated, which in a single experiment performs 36 parallel biochemical reactions with 36 different combinations of two reagents in stepwise concentration gradients. … Continue reading

Research Article: Characterising Complex Enzyme Reaction Data

Date Published: February 3, 2016 Publisher: Public Library of Science Author(s): Handan Melike Dönertaş, Sergio Martínez Cuesta, Syed Asad Rahman, Janet M. Thornton, Narayanaswamy Srinivasan. http://doi.org/10.1371/journal.pone.0147952 Abstract: The relationship between enzyme-catalysed reactions and the Enzyme Commission (EC) number, the widely accepted classification scheme used to characterise enzyme activity, is complex and with the rapid increase … Continue reading

Research Article: Insights into the Motif Preference of APOBEC3 Enzymes

Date Published: January 31, 2014 Publisher: Public Library of Science Author(s): Diako Ebrahimi, Hamid Alinejad-Rokny, Miles P. Davenport, Peter Sommer. http://doi.org/10.1371/journal.pone.0087679 Abstract: We used a multivariate data analysis approach to identify motifs associated with HIV hypermutation by different APOBEC3 enzymes. The analysis showed that APOBEC3G targets G mainly within GG, TG, TGG, GGG, TGGG and … Continue reading

Research Article: Interfacial Polymerization for Colorimetric Labeling of Protein Expression in Cells

Date Published: December 23, 2014 Publisher: Public Library of Science Author(s): Jacob L. Lilly, Phillip R. Sheldon, Liv J. Hoversten, Gabriela Romero, Vivek Balasubramaniam, Brad J. Berron, Daniel Rittschof. http://doi.org/10.1371/journal.pone.0115630 Abstract: Determining the location of rare proteins in cells typically requires the use of on-sample amplification. Antibody based recognition and enzymatic amplification is used to … Continue reading