Research Highlights: Fetal Alcohol Spectrum Disorder

Facial abnormalities associated with fetal alcohol syndrome and alcohol-related birth defects. Image Source: https://sites.duke.edu/apep/module-5-alcohol-and-babies/content-what-are-fetal-alcohol-spectrum-disorders/ Original Article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756137/ The unfavorable effects of alcohol consumption during pregnancy have long been known. A formal description and clinical diagnosis of these effects was in 1973. The distinction of the wide range of effects that can be caused by prenatal … Continue reading Research Highlights: Fetal Alcohol Spectrum Disorder

Research Highlights: Genes Related to the Development of Alcoholism

Image Source: Sebastian Hernandez/UCLA. https://newsroom.ucla.edu/releases/drug-shows-promise-for-treating-alcoholism Genetic factors account for a considerable portion of the risk for alcoholism. It is challenging to identify those genes and the specific variations. Case-control and family studies were used to identify genes related to the risk for alcohol. Different strategies such as candidate gene analyses and genome-wide association studies have … Continue reading Research Highlights: Genes Related to the Development of Alcoholism

Research Highlights: Treatment for White Blood Cell Malignancies Causes Nervous System Toxicity

Image Source: https://doi.org/10.1016/j.cell.2020.08.022 Original Article: https://doi.org/10.1016/j.cell.2020.08.022 The human CD19 antigen is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. CD19 is critically involved in establishing intrinsic B cell signaling thresholds through modulating both B cell receptor-dependent and independent signaling. CD19-directed immunotherapies are clinically effective for treating B cell malignancies but also cause a high incidence … Continue reading Research Highlights: Treatment for White Blood Cell Malignancies Causes Nervous System Toxicity

Research Highlights: Lithocholic Acid Alters Mitochondria Making Yeast Live Longer

Image Source: https://plantandmicrobiology.berkeley.edu/ Original Article: https://doi.org/10.18632/aging.100578 Lithocholic acid is a class of organic compounds known as monohydroxy bile acids, alcohols and derivatives, and has been found in human hepatic tissue, intestine and liver tissues, and has also been primarily detected in bile, feces, urine, and blood. This study revealed that lithocholic acid is a strong … Continue reading Research Highlights: Lithocholic Acid Alters Mitochondria Making Yeast Live Longer

Research Highlights: Macrophages Pick-up “Trash” from Heart Muscles

Image Source: https://www.vet.cornell.edu/ Original Article: https://doi.org/10.1016/j.cell.2020.08.031 Cardiomyocytes are the cells responsible for generating contractile force in the intact heart. Cardiomyocytes are subjected to the intense mechanical stress and metabolic demands of the beating heart. Cardiomyocytes are long-lived and rarely renewed. It is unclear whether these cardiomyocytes manage to preserve homeostasis on their own. Researchers discovered … Continue reading Research Highlights: Macrophages Pick-up “Trash” from Heart Muscles

Research Highlights: KPTN Gene Linked to Brain-Related Disorder

Image Source: https://www.researchgate.net/figure/Clinical-picture-macrocephaly_fig1_316703554 Original Article: http://doi.org/10.1016/j.ajhg.2013.10.001 The proper development of neuronal circuits during neuromorphogenesis and neuronal-network formation is critically dependent on a coordinated and intricate series of molecular and cellular cues and responses. Although the cortical actin cytoskeleton is known to play a key role in neuromorphogenesis, relatively little is known about the specific molecules … Continue reading Research Highlights: KPTN Gene Linked to Brain-Related Disorder

Research Highlights: The Role of Small RNAs in the Production of Blood Cells

Image Source: https://www.mit.edu/ Original Article: http://doi.org/10.1155/2013/695754 Hematopoiesis is the process by which the body produces blood cells and blood plasma. Blood cells are divided into three lineages: erythriod (erythrocytes), lymphoid (B and T cells), and myeloid (granulocytes, megakaryocytes, and macrophages). Haematopoiesis is a complex process regulated by several mechanisms including microRNAs (miRNAs). miRNAs are small … Continue reading Research Highlights: The Role of Small RNAs in the Production of Blood Cells

Research Highlights: High Immune Cell Count Associated with Low IQ in Children with HIV

Image Source: https://news.mit.edu/ Original Article: http://doi.org/10.1186/1742-6405-11-7 The human immunodeficiency virus (HIV) is an enveloped retrovirus that contains 2 copies of a single-stranded RNA genome. HIV causes the acquired immunodeficiency syndrome (AIDS) that is the last stage of HIV disease. HIV causes neurocognitive impairment possibly by transmigration through the blood brain barrier of activated T cells and … Continue reading Research Highlights: High Immune Cell Count Associated with Low IQ in Children with HIV

News Highlights: Possible Life On The Planet Venus

The planet Venus. Image Source: https://www.uoregon.edu/ September 14, 2020 Phosphine is colorless repulsive-smelling gas of hydrogen and phosphorus, similar to ammonia, usually used as a fumigant to repel insects in agriculture. Venus is the second planet from the sun, with a surface very high in temperature and covered with clouds. Researchers detected phosphine molecules in … Continue reading News Highlights: Possible Life On The Planet Venus