Date Published: June 24, 2013 Publisher: Public Library of Science Author(s): Susanna M. Wallerstedt, Johan Fastbom, Kristina Johnell, Christina Sjöberg, Sten Landahl, Anders Sundström, Luis Eduardo M. Quintas. http://doi.org/10.1371/journal.pone.0067088 Abstract An association has been found between multi-dose drug dispensing (MDD) and use of many drugs. The aim of this study was to investigate the nature … Continue reading Research Article: Drug Treatment in Older People before and after the Transition to a Multi-Dose Drug Dispensing System–A Longitudinal Analysis

Date Published: October 31, 2011 Publisher: Public Library of Science Author(s): Christina Sjöberg, Christina Edward, Johan Fastbom, Kristina Johnell, Sten Landahl, Kristina Narbro, Susanna Maria Wallerstedt, Giuseppe Biondi-Zoccai. http://doi.org/10.1371/journal.pone.0026574 Abstract: In the elderly in Scandinavia, multi-dose drug dispensing (MDD) is a common alternative to ordinary prescriptions (OP). MDD patients receive their drugs in unit bags, one … Continue reading Research Article: Association between Multi-Dose Drug Dispensing and Quality of Drug Treatment – A Register-Based Study

Date Published: August 28, 2019 Publisher: Public Library of Science Author(s): Amand F. Schmidt, Hiddo J. L. Heerspink, Petra Denig, Chris Finan, Rolf H. H. Groenwold, Miguel Angel Luque-Fernandez. http://doi.org/10.1371/journal.pone.0221209 Abstract Increasingly, genetic analyses are conducted using information from subjects with established disease, who often receive concomitant treatment. We determined when treatment may bias genetic … Continue reading Research Article: When drug treatments bias genetic studies: Mediation and interaction

Date Published: August 18, 2006 Publisher: Public Library of Science Author(s): Samuel Dunyo, Paul Milligan, Tansy Edwards, Colin Sutherland, Geoffrey Targett, Margaret Pinder Abstract: ObjectivesTreatment of Plasmodium falciparum malaria with sulfadoxine-pyrimethamine (SP) is followed by a sharp rise in the prevalence and density of gametocytes. We did a randomized trial to determine the effect of … Continue reading Research Article: Gametocytaemia after Drug Treatment of Asymptomatic Plasmodium falciparum

Date Published: June 3, 2010 Publisher: Public Library of Science Author(s): Joseph Peter Torella, Remy Chait, Roy Kishony, Philip E. Bourne Abstract: The rapid proliferation of antibiotic-resistant pathogens has spurred the use of drug combinations to maintain clinical efficacy and combat the evolution of resistance. Drug pairs can interact synergistically or antagonistically, yielding inhibitory effects … Continue reading Research Article: Optimal Drug Synergy in Antimicrobial Treatments

Date Published: January 22, 2013 Publisher: Public Library of Science Author(s): Kathleen Vincent, Joseph S. Tauskela, Geoffrey A. Mealing, Jean-Philippe Thivierge, Rossella Rota. http://doi.org/10.1371/journal.pone.0054478 Abstract Preconditioning is defined as a range of stimuli that allow cells to withstand subsequent anaerobic and other deleterious conditions. While cell protection under preconditioning is well established, this paper investigates the … Continue reading Research Article: Altered Network Communication Following a Neuroprotective Drug Treatment

Date Published: September 14, 2011 Publisher: Public Library of Science Author(s): Ana Carvalho, Sara K. Olson, Edgar Gutierrez, Kelly Zhang, Lisa B. Noble, Esther Zanin, Arshad Desai, Alex Groisman, Karen Oegema, Ben Lehner. http://doi.org/10.1371/journal.pone.0024656 Abstract: Genetic and genome-wide RNAi approaches available in C. elegans, combined with tools for visualizing subcellular events with high-resolution, have led to … Continue reading Research Article: Acute Drug Treatment in the Early C. elegans Embryo

Date Published: April 27, 2018 Publisher: Public Library of Science Author(s): Kiva Ariani Fisher, Laura Michele Cahill, Stephanie Broyles, Marion Rorke, William Thomas Robinson, Georgios Κ Nikolopoulos. http://doi.org/10.1371/journal.pone.0196157 Abstract High-risk injection related behavior including use of non-sterile syringes is associated with negative health outcomes among people who inject drugs (PWID). Drug treatment programs have been … Continue reading Research Article: Knowledge of hepatitis C status moderates the relationship between history of drug treatment and sterile syringe use

Date Published: June 6, 2012 Publisher: Public Library of Science Author(s): Andrew S. Bell, Silvie Huijben, Krijn P. Paaijmans, Derek G. Sim, Brian H. K. Chan, William A. Nelson, Andrew F. Read, Steffen Borrmann. http://doi.org/10.1371/journal.pone.0037172 Abstract The evolution of drug resistant Plasmodium parasites is a major challenge to effective malaria control. In theory, competitive interactions between … Continue reading Research Article: Enhanced Transmission of Drug-Resistant Parasites to Mosquitoes following Drug Treatment in Rodent Malaria

Date Published: November 3, 2011 Publisher: Public Library of Science Author(s): Cheikh Loucoubar, Bronner Goncalves, Adama Tall, Cheikh Sokhna, Jean-François Trape, Fatoumata Diène Sarr, Joseph Faye, Abdoulaye Badiane, Alioune Badara Ly, Aliou Diop, Avner Bar-Hen, Jean-François Bureau, Anavaj Sakuntabhai, Richard Paul, Jose Antonio Stoute. http://doi.org/10.1371/journal.pone.0026364 Abstract: Despite considerable success of genome wide association (GWA) studies in … Continue reading Research Article: Impact of Changing Drug Treatment and Malaria Endemicity on the Heritability of Malaria Phenotypes in a Longitudinal Family-Based Cohort Study