Research Article: Cancer in Families

Date Published: December 28, 2004 Publisher: Public Library of Science Author(s): unknown Abstract: None Partial Text: The Icelandic population is now a part of a unique epidemiological study, which has involved investigating the genetic heritage of many of them. The reason that this experiment can be done is because of the remarkable records that exist … Continue reading Research Article: Cancer in Families

Research Article: Cancer Biomarker Discovery: The Entropic Hallmark

Date Published: August 18, 2010 Publisher: Public Library of Science Author(s): Regina Berretta, Pablo Moscato, William C. S. Cho. http://doi.org/10.1371/journal.pone.0012262 Abstract: It is a commonly accepted belief that cancer cells modify their transcriptional state during the progression of the disease. We propose that the progression of cancer cells towards malignant phenotypes can be efficiently tracked using … Continue reading Research Article: Cancer Biomarker Discovery: The Entropic Hallmark

Research Article: Cancer Reduces Transcriptome Specialization

Date Published: May 3, 2010 Publisher: Public Library of Science Author(s): Octavio Martínez, M. Humberto Reyes-Valdés, Luis Herrera-Estrella, Shin-Han Shiu. http://doi.org/10.1371/journal.pone.0010398 Abstract: A central goal of cancer biology is to understand how cells from this family of genetic diseases undergo specific morphological and physiological changes and regress to a de-regulated state of the cell cycle. The … Continue reading Research Article: Cancer Reduces Transcriptome Specialization

Research Article: Cancer-Drug Associations: A Complex System

Date Published: April 2, 2010 Publisher: Public Library of Science Author(s): Ertugrul Dalkic, Xuewei Wang, Neil Wright, Christina Chan, Jörg Hoheisel. http://doi.org/10.1371/journal.pone.0010031 Abstract: Network analysis has been performed on large-scale medical data, capturing the global topology of drugs, targets, and disease relationships. A smaller-scale network is amenable to a more detailed and focused analysis of the … Continue reading Research Article: Cancer-Drug Associations: A Complex System

Research Article: Cancer epigenetics: Moving forward

Date Published: June 7, 2018 Publisher: Public Library of Science Author(s): Angela Nebbioso, Francesco Paolo Tambaro, Carmela Dell’Aversana, Lucia Altucci, John M. Greally Abstract: Defects in chromatin modifiers and remodelers have been described both for hematological and solid malignancies, corroborating and strengthening the role of epigenetic aberrations in the etiology of cancer. Furthermore, epigenetic marks—DNA … Continue reading Research Article: Cancer epigenetics: Moving forward

Research Article: Cancer-Associated Fibroblasts Promote Proliferation of Endometrial Cancer Cells

Date Published: July 26, 2013 Publisher: Public Library of Science Author(s): Kavita S. Subramaniam, Seng Tian Tham, Zahurin Mohamed, Yin Ling Woo, Noor Azmi Mat Adenan, Ivy Chung, John W Glod. http://doi.org/10.1371/journal.pone.0068923 Abstract Endometrial cancer is the most commonly diagnosed gynecologic malignancy worldwide; yet the tumor microenvironment, especially the fibroblast cells surrounding the cancer cells, is … Continue reading Research Article: Cancer-Associated Fibroblasts Promote Proliferation of Endometrial Cancer Cells

Research Article: Cancer trials in sub-Saharan Africa: Aligning research and care

Date Published: July 10, 2017 Publisher: Public Library of Science Author(s): Satish Gopal Abstract: Satish Gopal discusses the challenges of deliverable cancer care and cancer trials in sub-Saharan Africa as well as a potential framework for overcoming these challenges. Partial Text: Cancer burden is increasing in sub-Saharan Africa (SSA), with more than 600,000 estimated new … Continue reading Research Article: Cancer trials in sub-Saharan Africa: Aligning research and care

Research Article: Cancer screening risk literacy of physicians in training: An experimental study

Date Published: July 3, 2019 Publisher: Public Library of Science Author(s): Dafina Petrova, Guiliana Mas, Gorka Navarrete, Tania Tello Rodriguez, Pedro J. Ortiz, Rocio Garcia-Retamero, Valerio Capraro. http://doi.org/10.1371/journal.pone.0218821 Abstract We investigated what factors may foster or hinder physicians’ cancer screening risk literacy–specifically the ability to understand evidence regarding screening effectiveness and make evidence-based recommendations to … Continue reading Research Article: Cancer screening risk literacy of physicians in training: An experimental study

Research Article: Cancer diagnosis through a tandem of classifiers for digitized histopathological slides

Date Published: January 16, 2019 Publisher: Public Library of Science Author(s): Daniel Lichtblau, Catalin Stoean, Marco Magalhaes. http://doi.org/10.1371/journal.pone.0209274 Abstract The current research study is concerned with the automated differentiation between histopathological slides from colon tissues with respect to four classes (healthy tissue and cancerous of grades 1, 2 or 3) through an optimized ensemble of … Continue reading Research Article: Cancer diagnosis through a tandem of classifiers for digitized histopathological slides