Research Article: Cancer in Families

Date Published: December 28, 2004 Publisher: Public Library of Science Author(s): unknown Abstract: None Partial Text: The Icelandic population is now a part of a unique epidemiological study, which has involved investigating the genetic heritage of many of them. The reason that this experiment can be done is because of the remarkable records that exist … Continue reading Research Article: Cancer in Families

Research Article: Cancer and Aging – the Inflammatory Connection

Date Published: October 1, 2017 Publisher: JKL International LLC Author(s): Adar Zinger, William C Cho, Arie Ben-Yehuda. http://doi.org/10.14336/AD.2016.1230 Abstract Aging and cancer are highly correlated biological phenomena. Various cellular processes such as DNA damage responses and cellular senescence that serve as tumor suppressing mechanisms throughout life result in degenerative changes and contribute to the aging … Continue reading Research Article: Cancer and Aging – the Inflammatory Connection

Research Article: Cancer Biomarker Discovery: The Entropic Hallmark

Date Published: August 18, 2010 Publisher: Public Library of Science Author(s): Regina Berretta, Pablo Moscato, William C. S. Cho. http://doi.org/10.1371/journal.pone.0012262 Abstract: It is a commonly accepted belief that cancer cells modify their transcriptional state during the progression of the disease. We propose that the progression of cancer cells towards malignant phenotypes can be efficiently tracked using … Continue reading Research Article: Cancer Biomarker Discovery: The Entropic Hallmark

Research Article: Cancer Reduces Transcriptome Specialization

Date Published: May 3, 2010 Publisher: Public Library of Science Author(s): Octavio Martínez, M. Humberto Reyes-Valdés, Luis Herrera-Estrella, Shin-Han Shiu. http://doi.org/10.1371/journal.pone.0010398 Abstract: A central goal of cancer biology is to understand how cells from this family of genetic diseases undergo specific morphological and physiological changes and regress to a de-regulated state of the cell cycle. The … Continue reading Research Article: Cancer Reduces Transcriptome Specialization

Research Article: Cancer-Drug Associations: A Complex System

Date Published: April 2, 2010 Publisher: Public Library of Science Author(s): Ertugrul Dalkic, Xuewei Wang, Neil Wright, Christina Chan, Jörg Hoheisel. http://doi.org/10.1371/journal.pone.0010031 Abstract: Network analysis has been performed on large-scale medical data, capturing the global topology of drugs, targets, and disease relationships. A smaller-scale network is amenable to a more detailed and focused analysis of the … Continue reading Research Article: Cancer-Drug Associations: A Complex System