Research Article: Colon Cryptogenesis: Asymmetric Budding

Date Published: October 21, 2013 Publisher: Public Library of Science Author(s): Chin Wee Tan, Yumiko Hirokawa, Bruce S. Gardiner, David W. Smith, Antony W. Burgess, Manlio Vinciguerra. http://doi.org/10.1371/journal.pone.0078519 Abstract The process of crypt formation and the roles of Wnt and cell-cell adhesion signaling in cryptogenesis are not well described; but are important to the understanding … Continue reading Research Article: Colon Cryptogenesis: Asymmetric Budding

Research Article: Colon cancer modulation by a diabetic environment: A single institutional experience

Date Published: March 2, 2017 Publisher: Public Library of Science Author(s): Isabel Prieto, Laura del Puerto-Nevado, Nieves Gonzalez, Sergio Portal-Nuñez, Sandra Zazo, Marta Corton, Pablo Minguez, Carmen Gomez-Guerrero, Jose Miguel Arce, Ana Belen Sanz, Sebastian Mas, Oscar Aguilera, Gloria Alvarez-Llamas, Pedro Esbrit, Alberto Ortiz, Carmen Ayuso, Jesus Egido, Federico Rojo, Jesus Garcia-Foncillas, Ajay Goel. http://doi.org/10.1371/journal.pone.0172300Continue reading Research Article: Colon cancer modulation by a diabetic environment: A single institutional experience

Research Article: Colon Cancer Tumorigenesis Initiated by the H1047R Mutant PI3K

Date Published: February 10, 2016 Publisher: Public Library of Science Author(s): Alexander E. Yueh, Susan N. Payne, Alyssa A. Leystra, Dana R. Van De Hey, Tyler M. Foley, Cheri A. Pasch, Linda Clipson, Kristina A. Matkowskyj, Dustin A. Deming, Qiang Wang. http://doi.org/10.1371/journal.pone.0148730 Abstract The phosphoinositide 3-kinase (PI3K) signaling pathway is critical for multiple important cellular … Continue reading Research Article: Colon Cancer Tumorigenesis Initiated by the H1047R Mutant PI3K

Research Article: Colon organoid formation and cryptogenesis are stimulated by growth factors secreted from myofibroblasts

Date Published: June 21, 2018 Publisher: Public Library of Science Author(s): Hon Yan Kelvin Yip, Chin Wee Tan, Yumiko Hirokawa, Antony Wilks Burgess, William B. Coleman. http://doi.org/10.1371/journal.pone.0199412 Abstract Although small intestinal epithelial stem cells form crypts when using intestinal culture conditions, colon stem cells usually form colonospheres. Colon mesenchymal cell feeder layers can stimulate colon … Continue reading Research Article: Colon organoid formation and cryptogenesis are stimulated by growth factors secreted from myofibroblasts

Research Article: Colon dysregulation in methamphetamine self-administering HIV-1 transgenic rats

Date Published: January 2, 2018 Publisher: Public Library of Science Author(s): Amanda L. Persons, Brinda D. Bradaric, Hemraj B. Dodiya, Michael Ohene-Nyako, Christopher B. Forsyth, Ali Keshavarzian, Maliha Shaikh, T. Celeste Napier, Shilpa J. Buch. http://doi.org/10.1371/journal.pone.0190078 Abstract The integrity and function of the gut is impaired in HIV-infected individuals, and gut pathogenesis may play a … Continue reading Research Article: Colon dysregulation in methamphetamine self-administering HIV-1 transgenic rats

Research Article: Colon Necrosis Due to Sodium Polystyrene Sulfonate with and without Sorbitol: An Experimental Study in Rats

Date Published: September 28, 2015 Publisher: Public Library of Science Author(s): Isabelle Ayoub, Man S. Oh, Raavi Gupta, Michael McFarlane, Anna Babinska, Moro O. Salifu, Luis Eduardo M Quintas. http://doi.org/10.1371/journal.pone.0137636 Abstract Based on a single rat study by Lillemoe et al, the consensus has been formed to implicate sorbitol rather than sodium polystyrene sulfonate (SPS) … Continue reading Research Article: Colon Necrosis Due to Sodium Polystyrene Sulfonate with and without Sorbitol: An Experimental Study in Rats

Research Article: Colon Cancer-Specific Antigen-2 May Be Used as a Detecting and Prognostic Marker in Colorectal Cancer: A Preliminary Observation

Date Published: April 7, 2014 Publisher: Public Library of Science Author(s): Gang Xue, Xiaojuan Wang, Yong Yang, Degui Liu, Ying Cheng, Jun Zhou, Yongkuan Cao, DunFa Peng. http://doi.org/10.1371/journal.pone.0094252 Abstract A specific and sensitive serum marker for colorectal cancer (CRC) detection and surveillance is central to effective treatment. It was preliminarily reported that some nuclear matrix … Continue reading Research Article: Colon Cancer-Specific Antigen-2 May Be Used as a Detecting and Prognostic Marker in Colorectal Cancer: A Preliminary Observation

Research Article: Colon Stem Cell and Crypt Dynamics Exposed by Cell Lineage Reconstruction

Date Published: July 28, 2011 Publisher: Public Library of Science Author(s): Yitzhak Reizel, Noa Chapal-Ilani, Rivka Adar, Shalev Itzkovitz, Judith Elbaz, Yosef E. Maruvka, Elad Segev, Liran I. Shlush, Nava Dekel, Ehud Shapiro, Marshall S. Horwitz Abstract: Stem cell dynamics in vivo are often being studied by lineage tracing methods. Our laboratory has previously developed … Continue reading Research Article: Colon Stem Cell and Crypt Dynamics Exposed by Cell Lineage Reconstruction

Research Article: Colon-Derived Liver Metastasis, Colorectal Carcinoma, and Hepatocellular Carcinoma Can Be Discriminated by the Ca2+-Binding Proteins S100A6 and S100A11

Date Published: December 2, 2008 Publisher: Public Library of Science Author(s): Christian Melle, Günther Ernst, Bettina Schimmel, Annett Bleul, Ferdinand von Eggeling, Joseph Alan Bauer. http://doi.org/10.1371/journal.pone.0003767 Abstract: It is unknown, on the proteomic level, whether the protein patterns of tumors change during metastasis or whether markers are present that allow metastases to be allocated to a … Continue reading Research Article: Colon-Derived Liver Metastasis, Colorectal Carcinoma, and Hepatocellular Carcinoma Can Be Discriminated by the Ca2+-Binding Proteins S100A6 and S100A11

Research Article: Focus on 16p13.3 Locus in Colon Cancer

Date Published: July 29, 2015 Publisher: Public Library of Science Author(s): Evi Mampaey, Annelies Fieuw, Thalia Van Laethem, Liesbeth Ferdinande, Kathleen Claes, Wim Ceelen, Yves Van Nieuwenhove, Piet Pattyn, Marc De Man, Kim De Ruyck, Nadine Van Roy, Karen Geboes, Stéphanie Laurent, Jörg D. Hoheisel. http://doi.org/10.1371/journal.pone.0131421 Abstract With one million new cases of colorectal cancer … Continue reading Research Article: Focus on 16p13.3 Locus in Colon Cancer