Research Article: Postmitotic Specification of Drosophila Insulinergic Neurons from Pioneer Neurons

Date Published: March 11, 2008 Publisher: Public Library of Science Author(s): Irene Miguel-Aliaga, Stefan Thor, Alex P Gould, Roel Nusse Abstract: Insulin and related peptides play important and conserved functions in growth and metabolism. Although Drosophila has proved useful for the genetic analysis of insulin functions, little is known about the transcription factors and cell … Continue reading Research Article: Postmitotic Specification of Drosophila Insulinergic Neurons from Pioneer Neurons

Research Article: Distribution of densin in neurons

Date Published: October 16, 2018 Publisher: Public Library of Science Author(s): Ayse Dosemeci, Jung-Hwa Tao-Cheng, Hannah Loo, Thomas S. Reese, Michelle M. Adams. http://doi.org/10.1371/journal.pone.0205859 Abstract Densin is a scaffold protein known to associate with key elements of neuronal signaling. The present study examines the distribution of densin at the ultrastructural level in order to reveal … Continue reading Research Article: Distribution of densin in neurons

Research Article: Channel Properties of Nax Expressed in Neurons

Date Published: May 11, 2015 Publisher: Public Library of Science Author(s): Masahito Matsumoto, Takeshi Y. Hiyama, Kazuya Kuboyama, Ryoko Suzuki, Akihiro Fujikawa, Masaharu Noda, Diego Alvarez de la Rosa. http://doi.org/10.1371/journal.pone.0126109 Abstract Nax is a sodium-concentration ([Na+])-sensitive Na channel with a gating threshold of ~150 mM for extracellular [Na+] ([Na+]o) in vitro. We previously reported that … Continue reading Research Article: Channel Properties of Nax Expressed in Neurons

Research Article: Stimulus Discrimination in Cerebellar Purkinje Neurons

Date Published: February 5, 2014 Publisher: Public Library of Science Author(s): Katharina Reusch, Noah A. Russell, Tomas C. Bellamy, Maurice J. Chacron. http://doi.org/10.1371/journal.pone.0087828 Abstract Cerebellar Purkinje neurons fire spontaneously in the absence of synaptic input. Overlaid on this intrinsic activity, excitatory input from parallel fibres can add simple spikes to the output train, whereas inhibitory … Continue reading Research Article: Stimulus Discrimination in Cerebellar Purkinje Neurons

Research Article: Neurofibromin 1 Is a miRNA Target in Neurons

Date Published: October 2, 2012 Publisher: Public Library of Science Author(s): Maria Paschou, Epaminondas Doxakis, Justin L. Mott. http://doi.org/10.1371/journal.pone.0046773 Abstract Mutations of the neurofibromin 1 gene cause neurofibromatosis type 1, a disease in which learning and behavioral abnormalities are common. The disease is completely penetrant but shows variable phenotypic expression in patients. The repertoire of regulatory … Continue reading Research Article: Neurofibromin 1 Is a miRNA Target in Neurons

Research Article: Orexin Neurons Receive Glycinergic Innervations

Date Published: September 16, 2011 Publisher: Public Library of Science Author(s): Mari Hondo, Naoki Furutani, Miwako Yamasaki, Masahiko Watanabe, Takeshi Sakurai, Kazutaka Ikeda. http://doi.org/10.1371/journal.pone.0025076 Abstract: Glycine, a nonessential amino-acid that acts as an inhibitory neurotransmitter in the central nervous system, is currently used as a dietary supplement to improve the quality of sleep, but its mechanism … Continue reading Research Article: Orexin Neurons Receive Glycinergic Innervations