acetylcholine receptor (AChR) | definition

  • membrane protein that facilitates the binding of acetylcholine
  • can be transmitted-gated ion channel (nicotinic AChR) or G-protein-coupled receptor (muscarinic AChR)
acetylcholine receptor
By Ataly – Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=8778716

Source:

Alberts, B., Johnson, A., Lewis, J., Morgan, D., Raf, M., Roberts, K., & Walter, P. (2015). Molecular Biology of the Cell. New York: Garland Science. http://www.garlandscience.com/

Advertisements
Advertisements

Related Research

Research Article: An Acetylcholine Receptor Keeps Muscles in Balance

Date Published: December 22, 2009 Publisher: Public Library of Science Author(s): Rachel Jones Abstract: None Partial Text: Muscle contraction is controlled by receptors in the muscle cell membranes that respond to the neurotransmitter acetylcholine when it is released from motor neurons. Acetylcholine receptors are also found on neurons, where they perform a variety of important … Continue reading

Research Article: A Neuronal Acetylcholine Receptor Regulates the Balance of Muscle Excitation and Inhibition in Caenorhabditis elegans

Date Published: December 22, 2009 Publisher: Public Library of Science Author(s): Maelle Jospin, Yingchuan B. Qi, Tamara M. Stawicki, Thomas Boulin, Kim R. Schuske, H. Robert Horvitz, Jean-Louis Bessereau, Erik M. Jorgensen, Yishi Jin, Hugo J. Bellen Abstract: The role of a heterotrimeric neuronal acetylcholine receptor in regulating a Caenorhabditis elegans locomotion circuit are revealed … Continue reading

Research Article: Molecular Recognition of the Neurotransmitter Acetylcholine by an Acetylcholine Binding Protein Reveals Determinants of Binding to Nicotinic Acetylcholine Receptors

Date Published: March 17, 2014 Publisher: Public Library of Science Author(s): Jeppe A. Olsen, Thomas Balle, Michael Gajhede, Philip K. Ahring, Jette S. Kastrup, Srikumar P. Chellappan. http://doi.org/10.1371/journal.pone.0091232 Abstract: Despite extensive studies on nicotinic acetylcholine receptors (nAChRs) and homologues, details of acetylcholine binding are not completely resolved. Here, we report the crystal structure of acetylcholine … Continue reading

Research Article: Functional Characterization of a Novel Class of Morantel-Sensitive Acetylcholine Receptors in Nematodes

Date Published: December 1, 2015 Publisher: Public Library of Science Author(s): Elise Courtot, Claude L. Charvet, Robin N. Beech, Abdallah Harmache, Adrian J. Wolstenholme, Lindy Holden-Dye, Vincent O’Connor, Nicolas Peineau, Debra J. Woods, Cedric Neveu, Raffi V. Aroian. http://doi.org/10.1371/journal.ppat.1005267 Abstract: Acetylcholine receptors are pentameric ligand–gated channels involved in excitatory neuro-transmission in both vertebrates and invertebrates. … Continue reading

Research Article: Crosslinking-Induced Endocytosis of Acetylcholine Receptors by Quantum Dots

Date Published: February 25, 2014 Publisher: Public Library of Science Author(s): Chi Wai Lee, Hailong Zhang, Lin Geng, H. Benjamin Peng, William Phillips. http://doi.org/10.1371/journal.pone.0090187 Abstract: In a majority of patients with myasthenia gravis (MG), anti-acetylcholine receptor (AChR) antibodies target postsynaptic AChR clusters and thus compromise the membrane integrity of neuromuscular junctions (NMJs) and lead to … Continue reading

Research Article: Radiating Amyloid Fibril Formation on the Surface of Lipid Membranes through Unit-Assembly of Oligomeric Species of α-Synuclein

Date Published: October 15, 2012 Publisher: Public Library of Science Author(s): Jung-Ho Lee, Chul-Suk Hong, Soonkoo Lee, Jee-Eun Yang, Yong Il Park, Daekyun Lee, Taeghwan Hyeon, Seunho Jung, Seung R. Paik, Patrick Lewis. http://doi.org/10.1371/journal.pone.0047580 Abstract: Lewy body in the substantia nigra is a cardinal pathological feature of Parkinson’s disease. Despite enormous efforts, the cause-and-effect relationship between … Continue reading