alternative RNA splicing | definition

  • the process by which different RNAs are produced from a single gene
  • the splicing of the transcript in different ways to form different RNAs

Source:

Alberts, B., Johnson, A., Lewis, J., Morgan, D., Raf, M., Roberts, K., & Walter, P. (2015). Molecular Biology of the Cell. New York: Garland Science. http://www.garlandscience.com/

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Related Research

Research Article: Global Profiling of the Cellular Alternative RNA Splicing Landscape during Virus-Host Interactions

Date Published: September 6, 2016 Publisher: Public Library of Science Author(s): Simon Boudreault, Camille Martenon-Brodeur, Marie Caron, Jean-Michel Garant, Marie-Pier Tremblay, Victoria E. S. Armero, Mathieu Durand, Elvy Lapointe, Philippe Thibault, Maude Tremblay-Létourneau, Jean-Pierre Perreault, Michelle S. Scott, Guy Lemay, Martin Bisaillon, Massimo Caputi. http://doi.org/10.1371/journal.pone.0161914 Abstract: Alternative splicing (AS) is a central mechanism of genetic … Continue reading

Research Article: Transcriptome-wide analysis of alternative RNA splicing events in Epstein-Barr virus-associated gastric carcinomas

Date Published: May 11, 2017 Publisher: Public Library of Science Author(s): Victoria E. S. Armero, Marie-Pier Tremblay, Andréa Allaire, Simon Boudreault, Camille Martenon-Brodeur, Cyntia Duval, Mathieu Durand, Elvy Lapointe, Philippe Thibault, Maude Tremblay-Létourneau, Jean-Pierre Perreault, Michelle S. Scott, Martin Bisaillon, Massimo Caputi. http://doi.org/10.1371/journal.pone.0176880 Abstract: Multiple human diseases including cancer have been associated with a dysregulation … Continue reading

Research Article: Myocardial Alternative RNA Splicing and Gene Expression Profiling in Early Stage Hypoplastic Left Heart Syndrome

Date Published: January 27, 2012 Publisher: Public Library of Science Author(s): Marco Ricci, Yanji Xu, Harriet L. Hammond, David A. Willoughby, Lubov Nathanson, Maria M. Rodriguez, Matteo Vatta, Steven E. Lipshultz, Joy Lincoln, Philippe Rouet. http://doi.org/10.1371/journal.pone.0029784 Abstract: Hypoplastic Left Heart Syndrome (HLHS) is a congenital defect characterized by underdevelopment of the left ventricle and pathological compensation … Continue reading

Research Article: Small Molecule Amiloride Modulates Oncogenic RNA Alternative Splicing to Devitalize Human Cancer Cells

Date Published: June 9, 2011 Publisher: Public Library of Science Author(s): Jan-Gowth Chang, Den-Mei Yang, Wen-Hsin Chang, Lu-Ping Chow, Wen-Ling Chan, Hui-Hua Lin, Hsien-Da Huang, Ya-Sian Chang, Cheng-Hao Hung, Wen-Kuang Yang, John D. Minna. http://doi.org/10.1371/journal.pone.0018643 Abstract: Alternative splicing involves differential exon selection of a gene transcript to generate mRNA and protein isoforms with structural and functional … Continue reading