aminoacyl-tRNA synthetase | definition

  • an enzyme that attaches the amino acid to a transfer RNA to form aminoacyl-tRNA


Alberts, B., Johnson, A., Lewis, J., Morgan, D., Raf, M., Roberts, K., & Walter, P. (2015). Molecular Biology of the Cell. New York: Garland Science.


Related Research

Research Article: Common Peptides Study of Aminoacyl-tRNA Synthetases

Date Published: May 27, 2011 Publisher: Public Library of Science Author(s): Assaf Gottlieb, Milana Frenkel-Morgenstern, Mark Safro, David Horn, I. King Jordan. Abstract: Aminoacyl tRNA synthetases (aaRSs) constitute an essential enzyme super-family, providing fidelity of the translation process of mRNA to proteins in living cells. They are common to all kingdoms and are of utmost … Continue reading

Research Article: MIST, a Novel Approach to Reveal Hidden Substrate Specificity in Aminoacyl-tRNA Synthetases

Date Published: June 11, 2015 Publisher: Public Library of Science Author(s): Gilbert Eriani, Joseph Karam, Jomel Jacinto, Erin Morris Richard, Renaud Geslain, Giovanni Maga. Abstract: Aminoacyl-tRNA synthetases (AARSs) constitute a family of RNA-binding proteins, that participate in the translation of the genetic code, by covalently linking amino acids to appropriate tRNAs. Due to their … Continue reading

Research Article: Natural Aminoacyl tRNA Synthetase Fragment Enhances Cardiac Function after Myocardial Infarction

Date Published: October 8, 2014 Publisher: Public Library of Science Author(s): Margaret E. McCormick, Mauricio Rojas, Tyler Moser-Katz, Ellie Tzima, John S. Reader, Toru Hosoda. Abstract: A naturally-occurring fragment of tyrosyl-tRNA synthetase (TyrRS) has been shown in higher eukaryotes to ‘moonlight’ as a pro-angiogenic cytokine in addition to its primary role in protein translation. … Continue reading

Research Article: Assembly of the Novel Five-Component Apicomplexan Multi-Aminoacyl-tRNA Synthetase Complex Is Driven by the Hybrid Scaffold Protein Tg-p43

Date Published: February 20, 2014 Publisher: Public Library of Science Author(s): Jason M. van Rooyen, Jean-Benjamin Murat, Pierre-Mehdi Hammoudi, Sylvie Kieffer-Jaquinod, Yohann Coute, Amit Sharma, Hervé Pelloux, Hassan Belrhali, Mohamed-Ali Hakimi, Ira J. Blader. Abstract: In Toxoplasma gondii, as in other eukaryotes, a subset of the amino-acyl-tRNA synthetases are arranged into an abundant cytoplasmic … Continue reading