aminoacyl-tRNA synthetase | definition

  • an enzyme that attaches the amino acid to a transfer RNA to form aminoacyl-tRNA

Source:

Alberts, B., Johnson, A., Lewis, J., Morgan, D., Raf, M., Roberts, K., & Walter, P. (2015). Molecular Biology of the Cell. New York: Garland Science. http://www.garlandscience.com/

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Date Published: May 27, 2011 Publisher: Public Library of Science Author(s): Assaf Gottlieb, Milana Frenkel-Morgenstern, Mark Safro, David Horn, I. King Jordan. http://doi.org/10.1371/journal.pone.0020361 Abstract: Aminoacyl tRNA synthetases (aaRSs) constitute an essential enzyme super-family, providing fidelity of the translation process of mRNA to proteins in living cells. They are common to all kingdoms and are of utmost … Continue reading

Research Article: MIST, a Novel Approach to Reveal Hidden Substrate Specificity in Aminoacyl-tRNA Synthetases

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Research Article: Natural Aminoacyl tRNA Synthetase Fragment Enhances Cardiac Function after Myocardial Infarction

Date Published: October 8, 2014 Publisher: Public Library of Science Author(s): Margaret E. McCormick, Mauricio Rojas, Tyler Moser-Katz, Ellie Tzima, John S. Reader, Toru Hosoda. http://doi.org/10.1371/journal.pone.0109325 Abstract: A naturally-occurring fragment of tyrosyl-tRNA synthetase (TyrRS) has been shown in higher eukaryotes to ‘moonlight’ as a pro-angiogenic cytokine in addition to its primary role in protein translation. … Continue reading

Research Article: Assembly of the Novel Five-Component Apicomplexan Multi-Aminoacyl-tRNA Synthetase Complex Is Driven by the Hybrid Scaffold Protein Tg-p43

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