anterior pituitary | definition

  • portion of the pituitary gland that produces six hormones
  • also called adenohypophysis


Clark, M., Douglas, M., Choi, J. Biology 2e. Houston, Texas: OpenStax. Access for free at:


Research Article: Cadmium Mimics Estrogen-Driven Cell Proliferation and Prolactin Secretion from Anterior Pituitary Cells

Date Published: November 13, 2013 Publisher: Public Library of Science Author(s): Sonia A. Ronchetti, Eliana A. Miler, Beatriz H. Duvilanski, Jimena P. Cabilla, Angel Nadal. Abstract: Cadmium (Cd) is a heavy metal of considerable occupational and environmental concern affecting wildlife and human health. Recent studies indicate that Cd, like other heavy metals, can mimic … Continue reading

Research Article: Roles of differential expression of miR-543-5p in GH regulation in rat anterior pituitary cells and GH3 cells

Date Published: September 11, 2019 Publisher: Public Library of Science Author(s): Ze-Wen Yu, Wei Gao, Xin-Yao Feng, Jin-Yu Zhang, Hai-Xiang Guo, Chang-Jiang Wang, Jian Chen, Jin-Ping Hu, Wen-Zhi Ren, Bao Yuan, Shao-Chen Sun. Abstract: Growth hormone (GH) is an important hormone released by the pituitary gland that plays a key role in the growth … Continue reading

Research Article: S100β-Positive Cells of Mesenchymal Origin Reside in the Anterior Lobe of the Embryonic Pituitary Gland

Date Published: October 3, 2016 Publisher: Public Library of Science Author(s): Kotaro Horiguchi, Hideji Yako, Saishu Yoshida, Ken Fujiwara, Takehiro Tsukada, Naoko Kanno, Hiroki Ueharu, Hiroto Nishihara, Takako Kato, Takashi Yashiro, Yukio Kato, Wenhui Hu. Abstract: The anterior and intermediate lobes of the pituitary gland develop through invagination of the oral ectoderm and as … Continue reading

Research Article: Expression and Activity of Acid-Sensing Ion Channels in the Mouse Anterior Pituitary

Date Published: December 15, 2014 Publisher: Public Library of Science Author(s): Jianyang Du, Leah R. Reznikov, Michael J. Welsh, Candice Askwith. Abstract: Acid sensing ion channels (ASICs) are proton-gated cation channels that are expressed in the nervous system and play an important role in fear learning and memory. The function of ASICs in the … Continue reading

Research Article: Characterization of the Mechanism of Inhibin α-Subunit Gene in Mouse Anterior Pituitary Cells by RNA Interference

Date Published: October 3, 2013 Publisher: Public Library of Science Author(s): Li Han, Canjie Wu, Hasan Riaz, Liya Bai, Jianguo Chen, Yanhong Zhen, Aizhen Guo, Liguo Yang, Rakesh N. Veedu. Abstract: Inhibin, a member of the transforming growth factor-β [TGF-β] superfamily, is a suppressor of follicle-stimulating hormone [FSH] release through pituitary–gonadal negative feedback loop … Continue reading

Research Article: Differentially Expressed miRNAs after GnRH Treatment and Their Potential Roles in FSH Regulation in Porcine Anterior Pituitary Cell

Date Published: February 22, 2013 Publisher: Public Library of Science Author(s): Rui-Song Ye, Qian-Yun Xi, Qien Qi, Xiao Cheng, Ting Chen, Hongyi Li, Sanpha Kallon, Gang Shu, Song-Bo Wang, Qing-Yan Jiang, Yong-Liang Zhang, Yoon Ki Kim. Abstract: Hypothalamic gonadotropin-releasing hormone (GnRH) is a major regulator of follicle-stimulating hormone (FSH) secretion in gonadotrope cell in the … Continue reading

Research Article: N-Terminal Prolactin-Derived Fragments, Vasoinhibins, Are Proapoptoptic and Antiproliferative in the Anterior Pituitary

Date Published: July 7, 2011 Publisher: Public Library of Science Author(s): Jimena Ferraris, Daniela Betiana Radl, Sandra Zárate, Gabriela Jaita, Guadalupe Eijo, Verónica Zaldivar, Carmen Clapp, Adriana Seilicovich, Daniel Pisera, Immo A. Hansen. Abstract: The anterior pituitary is under a constant cell turnover modulated by gonadal steroids. In the rat, an increase in the rate … Continue reading

Research Article: Differentiation capacities of PS-clusters, adult pituitary stem/progenitor cell clusters located in the parenchymal-niche, of the rat anterior lobe

Date Published: April 23, 2018 Publisher: Public Library of Science Author(s): Saishu Yoshida, Naoto Nishimura, Hideaki Yurino, Masaaki Kobayashi, Kotaro Horiguchi, Kentaro Yano, Shin-ichi Hashimoto, Takako Kato, Yukio Kato, Wenhui Hu. Abstract: Pituitary endocrine cells are supplied by Sox2-expressing stem/progenitor cells in the anterior lobe of the adult pituitary. In relation to their microenvironment … Continue reading

Research Article: Nitric Oxide Plays a Key Role in Ovariectomy-Induced Apoptosis in Anterior Pituitary: Interplay between Nitric Oxide Pathway and Estrogen

Date Published: September 9, 2016 Publisher: Public Library of Science Author(s): Sonia A. Ronchetti, Leticia I. Machiavelli, Fernanda A. Quinteros, Beatriz H. Duvilanski, Jimena P. Cabilla, Marco Colasanti. Abstract: Changes in the estrogenic status produce deep changes in pituitary physiology, mainly because estrogens (E2) are one of the main regulators of pituitary cell population. … Continue reading

Research Article: Regulation of Intestinal Immune Response by Selective Removal of the Anterior, Posterior, or Entire Pituitary Gland in Trichinella spiralis Infected Golden Hamsters

Date Published: March 15, 2013 Publisher: Public Library of Science Author(s): Rosalía Hernández-Cervantes, Andrés Quintanar-Stephano, Norma Moreno-Méndoza, Lorena López-Griego, Valeria López-Salazar, Romel Hernández-Bello, Julio César Carrero, Jorge Morales-Montor, Josep Bassaganya-Riera. Abstract: The influence of anterior pituitary hormones on the gastrointestinal tract of humans and animals has been previously reported. Hypophysectomy (HYPOX) in the rat causes … Continue reading