ataxia telangiectasia mutated protein (ATM) | definition

  • protein kinase that gets activated in response to breaks in double-strand DNA
  • activates a signal cascade which can lead to cell cycle arrest

Source:

Alberts, B., Johnson, A., Lewis, J., Morgan, D., Raf, M., Roberts, K., & Walter, P. (2015). Molecular Biology of the Cell. New York: Garland Science. http://www.garlandscience.com/

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