Highlights: Phase 1/2 Study of COVID-19 RNA Vaccine BNT162b1 in Adults

Image Source: https://news.virginia.edu/ 12 August 2020 In March 2020, the World Health Organization (WHO) declared a pandemic of coronavirus disease 2019 (COVID-19). The causative agent of COVID-19 is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A vaccine is urgently needed due to the rising cases and deaths reported globally. This study reports the available … Continue reading Highlights: Phase 1/2 Study of COVID-19 RNA Vaccine BNT162b1 in Adults

Coronavirus E-Protein As Potential Vaccine Target

Image Source: https://www.utsouthwestern.edu/ Coronaviruses have four main structural proteins, nucleocapsid protein (N), spike protein (S), membrane protein (M), and envelope protein (E). The E-protein is the smallest of all the structural proteins and is involved in a wide spectrum of functional collection. It comprises of three domains, short hydrophilic N-terminus domain, hydrophobic transmembrane domain, and … Continue reading Coronavirus E-Protein As Potential Vaccine Target

Highlights: SARS-CoV-2 E-Protein Structural Insight: A Potential Target for Vaccine Development and other Therapeutic Strategies

Image Source: https://doi.org/10.1371/journal.pone.0237300 August 12, 2020 The outbreak of COVID-19 across the world has posed unparalleled and global challenges on multiple fronts. Most of the vaccine and drug development has focused on the spike proteins and viral RNA-polymerases and main protease for viral replication. Using the bioinformatics and structural modelling approach, the study modeled the … Continue reading Highlights: SARS-CoV-2 E-Protein Structural Insight: A Potential Target for Vaccine Development and other Therapeutic Strategies

The Use of MiniPCR in the COVID-19 Pandemic

Image source: https://www.minipcr.com/ https://www.youtube.com/embed/ALNZJhUOSMs August 13, 2020 Recent epidemic events such as Zika in Southeast Asia and Latin-America in 2016, Ebola in West Africa in 2013–2015, and pandemic Influenza A/H1N1/2009 have clearly showed the urgent need for inexpensive, portable, and easy-to-use diagnostic systems that can be effectively deployable to address epidemic episodes. These portable diagnostic … Continue reading The Use of MiniPCR in the COVID-19 Pandemic

Highlights: Combined Use of the MiniPCR Thermocycler and a Well-Plate Reader As An Alternative COVID-19 Virus Detection

Image Source: https://collaborate.hms.harvard.edu/display/Hinton/Lab+5+DNA+Analysis The research article was published on August 13, 2020.The COVID-19 pandemic has crudely showed the need for huge and rapid diagnostics.More than 10 million positive cases of COVID-19 have been reported around the world on the early weeks of July 2020.In the case of an epidemic emergency, the first line of response … Continue reading Highlights: Combined Use of the MiniPCR Thermocycler and a Well-Plate Reader As An Alternative COVID-19 Virus Detection

Highlights: 10-Year Retrospective Study of Infectious Endophthalmitis At A Philippine Tertiary Hospital

Image Source: https://medicine.uiowa.edu/eye/ A research was published on 14 August 2020 about the infectious endophthalmitis.Endophthalmitis is a sight-threatening disease characterized by marked progressive inflammation of the vitreous and/or aqueous humors.There is a lack information regarding endophthalmitis in the Philippines.The study aimed to provide long-term summary data on endophthalmitis cases seen at the largest tertiary referral … Continue reading Highlights: 10-Year Retrospective Study of Infectious Endophthalmitis At A Philippine Tertiary Hospital

Highlights: Semen Microbiome, Sperm Impact, and Male Fertility

Image by Gerd Altmann from Pixabay PMID: 32794312 DOI: 10.1111/andr.12886 Male factor is regarded as being the cause of up to 50 percent of cases of infertility.Studies demonstrate that bacteria can affect sperm function negatively.Utilizing the next-generation sequencing (NGS) techniques have provided a better understanding of the human microbiome.Dysbiosis has been reported to impact health.Dysbiosis is a … Continue reading Highlights: Semen Microbiome, Sperm Impact, and Male Fertility

Highlights: Expired N95 Respirators and Used But Sterilized N95 Respirators Can Be Used As An Alternatives

Image Source: https://news.stanford.edu/ Acquiring respiratory protection for doctors and other health care workers has become a major challenge of the COVID-19 pandemic.This major challenge resulted in nonstandard practices such as the use of expired respirators and various sterilization processes to extend the useful life of respirators in health care settings.Due to the limited supply of … Continue reading Highlights: Expired N95 Respirators and Used But Sterilized N95 Respirators Can Be Used As An Alternatives

Highlights: Vitamin D Deficiency As A Predictor of Poor Prognosis in Patients with Acute Respiratory Failure Due to COVID-19

Image by silviarita from Pixabay Research Info: 2020 Aug 9. doi: 10.1007/s40618-020-01370-xVitamin D deficiency is a highly spread condition associated with increased risk of respiratory tract infections.Cytokine storm is associated with disease severity.The goal of this research is to analyze vitamin D levels in patients with acute respiratory failure due to COVID-19 and to determine any … Continue reading Highlights: Vitamin D Deficiency As A Predictor of Poor Prognosis in Patients with Acute Respiratory Failure Due to COVID-19