axoneme | definition

  • a cytoskeletal structure made of microtubules and proteins that forms the central part of a cilium or flagellum
  • responsible for cell movements
Axoneme. Schematic diagram of the flagellar axoneme in cross-section. Structures that are discussed in this Commentary are highlighted. The details of the CP complex are based on the work of Mitchell (Mitchell, 2003a). Reprinted from Lindemann (Lindemann, 2007) with permission. DRC, dynein regulatory complex.


Alberts, B., Johnson, A., Lewis, J., Morgan, D., Raf, M., Roberts, K., & Walter, P. (2015). Molecular Biology of the Cell. New York: Garland Science.


Related Research

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Date Published: November 15, 2016 Publisher: Public Library of Science Author(s): Giovanna Alfano, Przemyslaw M. Kruczek, Amna Z. Shah, Barbara Kramarz, Glen Jeffery, Andrew C. Zelhof, Shomi S. Bhattacharya, Hemant Khanna. Abstract: Mutations in the EYS gene are a common cause of autosomal recessive retinitis pigmentosa (arRP), yet the role of the EYS protein … Continue reading

Research Article: Ofd1 Controls Dorso-Ventral Patterning and Axoneme Elongation during Embryonic Brain Development

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Research Article: Space-Dependent Formation of Central Pair Microtubules and Their Interactions with Radial Spokes

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Related External Links

Crystal structure of human PACRG in complex with MEIG1 reveals roles in axoneme formation and tubulin binding.

Khan N, Pelletier D, McAlear TS, Croteau N, Veyron S, Bayne AN, Black C, Ichikawa M, Khalifa AAZ, Chaaban S, Kurinov I, Brouhard G, Bechstedt S, Bui KH, Trempe JF.Structure. 2021 Jan 25:S0969-2126(21)00001-0. doi: 10.1016/j.str.2021.01.001. Online ahead of print.PMID: 33529594