beta cell | definition

endocrine cell of the pancreatic islets that produces the hormone insulin


Source:

Clark, M., Douglas, M., Choi, J. Biology 2e. Houston, Texas: OpenStax. Access for free at: https://openstax.org/details/books/biology-2e

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Research Article: Beta Cell Count Instead of Beta Cell Mass to Assess and Localize Growth in Beta Cell Population following Pancreatic Duct Ligation in Mice

Date Published: August 30, 2012 Publisher: Public Library of Science Author(s): Marie Chintinne, Geert Stangé, Bart Denys, Zhidong Ling, Peter In ‘t Veld, Daniel Pipeleers, Francis C. Lynn. http://doi.org/10.1371/journal.pone.0043959 Abstract: Pancreatic-tail duct ligation (PDL) in adult rodents has been reported to induce beta cell generation and increase beta cell mass but increases in beta cell number … Continue reading

Research Article: Circulating microRNA-375 as biomarker of pancreatic beta cell death and protection of beta cell mass by cytoprotective compounds

Date Published: October 17, 2017 Publisher: Public Library of Science Author(s): Imane Song, Sarah Roels, Geert A. Martens, Luc Bouwens, Massimo Pietropaolo. http://doi.org/10.1371/journal.pone.0186480 Abstract: Previous studies demonstrated that circulating microRNA-375 (miR-375) is a suitable plasma biomarker for real-time detection of beta cell death. The present study evaluated the use of this biomarker to assess the … Continue reading

Research Article: Circulating microRNA-375 as biomarker of pancreatic beta cell death and protection of beta cell mass by cytoprotective compounds

Date Published: October 17, 2017 Publisher: Public Library of Science Author(s): Imane Song, Sarah Roels, Geert A. Martens, Luc Bouwens, Massimo Pietropaolo. http://doi.org/10.1371/journal.pone.0186480 Abstract: Previous studies demonstrated that circulating microRNA-375 (miR-375) is a suitable plasma biomarker for real-time detection of beta cell death. The present study evaluated the use of this biomarker to assess the … Continue reading

Research Article: Human Fucci Pancreatic Beta Cell Lines: New Tools to Study Beta Cell Cycle and Terminal Differentiation

Date Published: September 26, 2014 Publisher: Public Library of Science Author(s): Géraldine Carlier, Alicia Maugein, Corinne Cordier, Séverine Pechberty, Meriem Garfa-Traoré, Patrick Martin, Raphaël Scharfmann, Olivier Albagli, Arun Rishi. http://doi.org/10.1371/journal.pone.0108202 Abstract: Regulation of cell cycle in beta cells is poorly understood, especially in humans. We exploited here the recently described human pancreatic beta cell line … Continue reading

Research Article: Glucose Regulates Rat Beta Cell Number through Age-Dependent Effects on Beta Cell Survival and Proliferation

Date Published: January 9, 2014 Publisher: Public Library of Science Author(s): Zerihun Assefa, Astrid Lavens, Christophe Steyaert, Geert Stangé, Geert A. Martens, Zhidong Ling, Karine Hellemans, Daniel Pipeleers, Marco Giorgio Baroni. http://doi.org/10.1371/journal.pone.0085174 Abstract: Glucose effects on beta cell survival and DNA-synthesis suggest a role as regulator of beta cell mass but data on beta cell … Continue reading

Research Article: Clusters of Conserved Beta Cell Marker Genes for Assessment of Beta Cell Phenotype

Date Published: September 2, 2011 Publisher: Public Library of Science Author(s): Geert A. Martens, Lei Jiang, Karine H. Hellemans, Geert Stangé, Harry Heimberg, Finn C. Nielsen, Olivier Sand, Jacques Van Helden, Frans K. Gorus, Daniel G. Pipeleers, Marc Tjwa. http://doi.org/10.1371/journal.pone.0024134 Abstract: The aim of this study was to establish a gene expression blueprint of pancreatic beta … Continue reading

Research Article: The Beta Cell in Its Cluster: Stochastic Graphs of Beta Cell Connectivity in the Islets of Langerhans

Date Published: August 12, 2015 Publisher: Public Library of Science Author(s): Deborah A. Striegel, Manami Hara, Vipul Periwal, Morten Gram Pedersen Abstract: Pancreatic islets of Langerhans consist of endocrine cells, primarily α, β and δ cells, which secrete glucagon, insulin, and somatostatin, respectively, to regulate plasma glucose. β cells form irregular locally connected clusters within … Continue reading

Research Article: Evaluation of the INS-1 832/13 Cell Line as a Beta-Cell Based Screening System to Assess Pollutant Effects on Beta-Cell Function

Date Published: March 21, 2013 Publisher: Public Library of Science Author(s): Tine L. M. Hectors, Caroline Vanparys, Anna Pereira-Fernandes, Geert A. Martens, Ronny Blust, Vincent Laudet. http://doi.org/10.1371/journal.pone.0060030 Abstract: Environmental pollutants have recently emerged as potential risk factors for metabolic diseases, urging systematic investigation of pollutant effects on metabolic disease processes. To enable risk assessment of these … Continue reading

Research Article: In Vitro Proliferation of Adult Human Beta-Cells

Date Published: April 26, 2012 Publisher: Public Library of Science Author(s): Sabine Rutti, Nadine S. Sauter, Karim Bouzakri, Richard Prazak, Philippe A. Halban, Marc Y. Donath, Kathrin Maedler. http://doi.org/10.1371/journal.pone.0035801 Abstract: A decrease in functional beta-cell mass is a key feature of type 2 diabetes. Glucagon-like peptide 1 (GLP-1) analogues induce proliferation of rodent beta-cells. However, the … Continue reading

Research Article: A proteomic signature that reflects pancreatic beta-cell function

Date Published: August 30, 2018 Publisher: Public Library of Science Author(s): Aoife M. Curran, Marie Pier Scott-Boyer, Jim Kaput, Miriam F. Ryan, Elaine Drummond, Eileen R. Gibney, Michael J. Gibney, Helen M. Roche, Lorraine Brennan, Corentin Cras-Méneur. http://doi.org/10.1371/journal.pone.0202727 Abstract: Proteomics has the potential to enhance early identification of beta-cell dysfunction, in conjunction with monitoring the … Continue reading

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