diabetes insipidus | definition

disorder caused by underproduction of ADH


Clark, M., Douglas, M., Choi, J. Biology 2e. Houston, Texas: OpenStax. Access for free at: https://openstax.org/details/books/biology-2e


Research Article: Diabetes Insipidus in Mice with a Mutation in Aquaporin-2

Date Published: August 19, 2005 Publisher: Public Library of Science Author(s): David J Lloyd, Frank Wesley Hall, Lisa M Tarantino, Nicholas Gekakis, David Beier Abstract: Congenital nephrogenic diabetes insipidus (NDI) is a disease characterized by failure of the kidney to concentrate urine in response to vasopressin. Human kindreds with nephrogenic diabetes insipidus have been found … Continue reading

Research Article: Signaling Modification by GPCR Heteromer and Its Implication on X-Linked Nephrogenic Diabetes Insipidus

Date Published: September 20, 2016 Publisher: Public Library of Science Author(s): Hans K. H. Ng, Kaleeckal G. Harikumar, Laurence J. Miller, Billy K. C. Chow, Giovanna Valenti. http://doi.org/10.1371/journal.pone.0163086 Abstract: The involvement of secretin (SCT) and secretin receptor (SCTR) in regulating body water homeostasis is well established. Identified as one of the vasopressin (Vp)-independent mechanisms in … Continue reading

Research Article: Absence of PKC-Alpha Attenuates Lithium-Induced Nephrogenic Diabetes Insipidus

Date Published: July 9, 2014 Publisher: Public Library of Science Author(s): Jae H. Sim, Nathaniel J. Himmel, Sara K. Redd, Fadi E. Pulous, Richard T. Rogers, Lauren N. Black, Seongun M. Hong, Tobias N. von Bergen, Mitsi A. Blount, Eric Feraille. http://doi.org/10.1371/journal.pone.0101753 Abstract: Lithium, an effective antipsychotic, induces nephrogenic diabetes insipidus (NDI) in ∼40% of … Continue reading