hyperkalemia | definition

  • higher-than-normal blood potassium levels
  • a condition where the potassium level in the blood is abnormally high


Betts, J. G., Young, K. A., Wise, J. A., Johnson, E., Poe, B., Kruse, D. H., … DeSaix, P. (n.d.). Anatomy and Physiology. Houston, Texas: OpenStax. Access for free at: https://openstax.org/details/books/anatomy-and-physiology


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Research Article: Predictors for repeated hyperkalemia and potassium trajectories in high-risk patients — A population-based cohort study

Date Published: June 21, 2019 Publisher: Public Library of Science Author(s): Kasper Adelborg, Sia Kromann Nicolaisen, Pål Hasvold, Eirini Palaka, Lars Pedersen, Reimar Wernich Thomsen, Gregory Shearer. http://doi.org/10.1371/journal.pone.0218739 Abstract Understanding predictors and trajectories of increased potassium may inform testing and treatment of hyperkalemia. We examined predictors for repeated hyperkalemia among patients after first-time renin angiotensin … Continue reading

Research Article: Long-term efficacy of oral calcium polystyrene sulfonate for hyperkalemia in CKD patients

Date Published: March 22, 2017 Publisher: Public Library of Science Author(s): Mi-Yeon Yu, Jee Hyun Yeo, Joon-Sung Park, Chang Hwa Lee, Gheun-Ho Kim, Tatsuo Shimosawa. http://doi.org/10.1371/journal.pone.0173542 Abstract Calcium polystyrene sulfonate (CPS) has long been used to treat hyperkalemia in patients with chronic kidney disease (CKD). However, its efficacy and safety profile have not been systematically … Continue reading

Research Article: Optimal Dose and Method of Administration of Intravenous Insulin in the Management of Emergency Hyperkalemia: A Systematic Review

Date Published: May 5, 2016 Publisher: Public Library of Science Author(s): Ziv Harel, Kamel S. Kamel, Pasqual Barretti. http://doi.org/10.1371/journal.pone.0154963 Abstract Hyperkalemia is a common electrolyte disorder that can result in fatal cardiac arrhythmias. Despite the importance of insulin as a lifesaving intervention in the treatment of hyperkalemia in an emergency setting, there is no consensus … Continue reading

Research Article: Low Potassium Dialysate as a Protective Factor of Sudden Cardiac Death in Hemodialysis Patients with Hyperkalemia

Date Published: October 6, 2015 Publisher: Public Library of Science Author(s): Chien-Wei Huang, Min-Jing Lee, Po-Tsang Lee, Chih-Yang Hsu, Wei-Chieh Huang, Chien-Liang Chen, Kang-Ju Chou, Hua-Chang Fang, Tatsuo Shimosawa. http://doi.org/10.1371/journal.pone.0139886 Abstract Hyperkalemia increases the risk of sudden cardiac death (SCD) in hemodialysis patients. Our objective was to determine the association between administering low potassium dialysate … Continue reading

Research Article: Cubozoan Venom-Induced Cardiovascular Collapse Is Caused by Hyperkalemia and Prevented by Zinc Gluconate in Mice

Date Published: December 12, 2012 Publisher: Public Library of Science Author(s): Angel A. Yanagihara, Ralph V. Shohet, Partha Mukhopadhyay. http://doi.org/10.1371/journal.pone.0051368 Abstract Chironex fleckeri (Australian box jellyfish) stings can cause acute cardiovascular collapse and death. We developed methods to recover venom with high specific activity, and evaluated the effects of both total venom and constituent porins at … Continue reading

Research Article: Hyperkalemia and renin-angiotensin aldosterone system inhibitor therapy in chronic kidney disease: A general practice-based, observational study

Date Published: March 7, 2019 Publisher: Public Library of Science Author(s): Min Jun, Meg J. Jardine, Vlado Perkovic, Quentin Pilard, Laurent Billot, Anthony Rodgers, Kris Rogers, Martin Gallagher, Patrick Barry Mark. http://doi.org/10.1371/journal.pone.0213192 Abstract Data on hyperkalemia frequency among chronic kidney disease (CKD) patients receiving renin-angiotensin aldosterone system inhibitors (RAASis) and its impact on subsequent RAASi … Continue reading

Research Article: Incidence of and risk factors for newly diagnosed hyperkalemia after hospital discharge in non-dialysis-dependent CKD patients treated with RAS inhibitors

Date Published: September 6, 2017 Publisher: Public Library of Science Author(s): Yuki Saito, Hiroyuki Yamamoto, Hideki Nakajima, Osamu Takahashi, Yasuhiro Komatsu, Ping-Hsun Wu. http://doi.org/10.1371/journal.pone.0184402 Abstract Renin-angiotensin system (RAS) inhibitors have been increasingly prescribed due to their beneficial effects on end-organ protection. Iatrogenic hyperkalemia is a well-known life-threatening complication of RAS inhibitor use in chronic kidney … Continue reading