Localization of Enzymes Within the Cell


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Organelles and structural order in metabolism. Organelles such as the mitochondrion (TEM) contain enzymes that carry out specific functions, in this case the second and third stages of cellular respiration.
Source: Urry, Lisa A.. Campbell Biology (p. 161). Pearson Education. Kindle Edition.

Localization of Enzymes Within the Cell (Campbell Biology)

The cell is not just a bag of chemicals with thousands of different kinds of enzymes and substrates in a random mix. The cell is compartmentalized, and cellular structures help bring order to metabolic pathways. In some cases, a team of enzymes for several steps of a metabolic pathway are assembled into a multi-enzyme complex. The arrangement facilitates the sequence of reactions, with the product from the first enzyme becoming the substrate for an adjacent enzyme in the complex, and so on, until the end product is released. Some enzymes and enzyme complexes have fixed locations within the cell and act as structural components of particular membranes. Others are in solution within particular membrane-enclosed eukaryotic organelles, each with its own internal chemical environment. For example, in eukaryotic cells, the enzymes for the second and third stages of cellular respiration reside in specific locations within mitochondria.


Urry, Lisa A.. Campbell Biology. Pearson Education. Kindle Edition. https://www.pearson.com/us/higher-education/series/Campbell-Biology-Series/2244849.html


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