mesangial cells | definition

  • contractile cells found in the glomerulus
  • can contract or relax to regulate filtration rate

Source:

Betts, J. G., Young, K. A., Wise, J. A., Johnson, E., Poe, B., Kruse, D. H., … DeSaix, P. (n.d.). Anatomy and Physiology. Houston, Texas: OpenStax. Access for free at: https://openstax.org/details/books/anatomy-and-physiology

Advertisements
Advertisements
Keywords: definition, define, what is, meaning, thesaurus, synonyms, dictionary, encyclopedia, research, research article, research study, scientific literature, science topic

Research Articles Related To Mesangial Cells

Research Article: Unique Regulatory Properties of Mesangial Cells Are Genetically Determined in the Rat

Date Published: October 24, 2014 Publisher: Public Library of Science Author(s): Ping-Chin Lai, Ling-Yin Chiu, Prashant Srivastava, Cristina Trento, Francesco Dazzi, Enrico Petretto, H. Terence Cook, Jacques Behmoaras, Niels Olsen Saraiva Câmara. http://doi.org/10.1371/journal.pone.0111452 Abstract Mesangial cells are glomerular cells of stromal origin. During immune complex mediated crescentic glomerulonephritis (Crgn), infiltrating and proliferating pro-inflammatory macrophages lead … Continue reading

Research Article: Sodium Glucose Cotransporter 2 (SGLT2) Plays as a Physiological Glucose Sensor and Regulates Cellular Contractility in Rat Mesangial Cells

Date Published: March 21, 2016 Publisher: Public Library of Science Author(s): Masanori Wakisaka, Tetsuhiko Nagao, Mototaka Yoshinari, Utpal Sen. http://doi.org/10.1371/journal.pone.0151585 Abstract Mesangial cells play an important role in regulating glomerular filtration by altering their cellular tone. We report the presence of a sodium glucose cotransporter (SGLT) in rat mesangial cells. This study in rat mesangial … Continue reading

Research Article: Synergistic Effect of Mesangial Cell-Induced CXCL1 and TGF-β1 in Promoting Podocyte Loss in IgA Nephropathy

Date Published: August 30, 2013 Publisher: Public Library of Science Author(s): Li Zhu, Qingxian Zhang, Sufang Shi, Lijun Liu, Jicheng Lv, Hong Zhang, Jean-Claude Dussaule. http://doi.org/10.1371/journal.pone.0073425 Abstract Podocyte loss has been reported to relate to disease severity and progression in IgA nephropathy (IgAN). However, the underlying mechanism for its role in IgAN remain unclear. Recent … Continue reading

Research Article: X-Linked Alport Dogs Demonstrate Mesangial Filopodial Invasion of the Capillary Tuft as an Early Event in Glomerular Damage

Date Published: December 13, 2016 Publisher: Public Library of Science Author(s): Sabrina D. Clark, Mary B. Nabity, Rachel E. Cianciolo, Brianna Dufek, Dominic Cosgrove, Alexander V. Ljubimov. http://doi.org/10.1371/journal.pone.0168343 Abstract X-linked Alport syndrome (XLAS), caused by mutations in the type IV collagen COL4A5 gene, accounts for approximately 80% of human Alport syndrome. Dogs with XLAS have … Continue reading

Research Article: A bigenic mouse model of FSGS reveals perturbed pathways in podocytes, mesangial cells and endothelial cells

Date Published: August 28, 2019 Publisher: Public Library of Science Author(s): Andrew S. Potter, Keri Drake, Eric W. Brunskill, S. Steven Potter, Peter Hohenstein. http://doi.org/10.1371/journal.pone.0216261 Abstract Focal segmental glomerulosclerosis is a major cause of end stage renal disease. Many patients prove unresponsive to available therapies. An improved understanding of the molecular basis of the disease … Continue reading

Research Article: Fenofibrate Attenuated Glucose-Induced Mesangial Cells Proliferation and Extracellular Matrix Synthesis via PI3K/AKT and ERK1/2

Date Published: October 9, 2013 Publisher: Public Library of Science Author(s): Rui Zeng, Yan Xiong, Fengming Zhu, Zufu Ma, Wenhui Liao, Yong He, JinSeng He, Wei Li, Juan Yang, Qian Lu, Gang Xu, Ying Yao, Effie C Tsilibary. http://doi.org/10.1371/journal.pone.0076836 Abstract Excess mesangial extracellular matrix (ECM) and mesangial cell proliferation is the major pathologic feature of diabetic … Continue reading

Research Article: Glycoxidised LDL Induced the Upregulation of Axl Receptor Tyrosine Kinase and Its Ligand in Mouse Mesangial Cells

Date Published: November 30, 2012 Publisher: Public Library of Science Author(s): Young Sook Kim, Dong Ho Jung, Eunjin Sohn, Junghyun Kim, Jin Sook Kim, Bridget Wagner. http://doi.org/10.1371/journal.pone.0050297 Abstract Low-density lipoprotein (LDL) is subjected to glycoxidation in diabetes, and a novel signalling mechanism by which glycoxidised LDL functions in glomerular mesangial cells remains to be ascertained. We … Continue reading

Research Article: AS101 Prevents Diabetic Nephropathy Progression and Mesangial Cell Dysfunction: Regulation of the AKT Downstream Pathway

Date Published: December 4, 2014 Publisher: Public Library of Science Author(s): Itay Israel Shemesh, Benaya Rozen-Zvi, Yona Kalechman, Uzi Gafter, Benjamin Sredni, Garyfalia Drossopoulou. http://doi.org/10.1371/journal.pone.0114287 Abstract Diabetic nephropathy (DN) is characterized by proliferation of mesangial cells, mesangial expansion, hypertrophy and extracellular matrix accumulation. Previous data have cross-linked PKB (AKT) to TGFβ induced matrix modulation. The … Continue reading

Research Article: Emodin Suppresses Hyperglycemia-Induced Proliferation and Fibronectin Expression in Mesangial Cells via Inhibiting cFLIP

Date Published: April 1, 2014 Publisher: Public Library of Science Author(s): Junjie Gao, Fangli Wang, Weisong Wang, Zhiguo Su, Canghui Guo, Shuyi Cao, Raghavan Raju. http://doi.org/10.1371/journal.pone.0093588 Abstract As one of the most serious microvascular complications of diabetes and a major cause of end stage renal disease, diabetic nephropathy (DN) is calling for effective treatment strategies. … Continue reading

Research Article: 6-Hydroxyflavone and Derivatives Exhibit Potent Anti-Inflammatory Activity among Mono-, Di- and Polyhydroxylated Flavones in Kidney Mesangial Cells

Date Published: March 19, 2015 Publisher: Public Library of Science Author(s): Xing Wang, Zhiwei Wang, Preetpal Singh Sidhu, Umesh R. Desai, Qibing Zhou, Salvatore V Pizzo. http://doi.org/10.1371/journal.pone.0116409 Abstract Inflammatory responses by kidney mesangial cells play a critical role in the glomerulonephritis. The anti-inflammatory potential of nineteen mono-, di- and polyhydroxylated flavones including fisetin, quercetin, morin, … Continue reading

Advertisements
Advertisements

Keywords: define mesangial cells, mesangial cells definition, what are mesangial cells, meaning of mesangial cells, mesangial cells, what are contractile cells in kidney