rapid eye movement (REM) sleep | definition

period of sleep characterized by brain waves very similar to those during wakefulness and by darting movements of the eyes under closed eyelids


Spielman, R. M., Jenkins, W. J., & Lovett, M. D. (2020). Psychology 2e. Houston, Texas: OpenStax. Access for free at https://openstax.org/details/books/psychology-2e


Research Article: Coupled Flip-Flop Model for REM Sleep Regulation in the Rat

Date Published: April 10, 2014 Publisher: Public Library of Science Author(s): Justin R. Dunmyre, George A. Mashour, Victoria Booth, Gennady Cymbalyuk. http://doi.org/10.1371/journal.pone.0094481 Abstract: Recent experimental studies investigating the neuronal regulation of rapid eye movement (REM) sleep have identified mutually inhibitory synaptic projections among REM sleep-promoting (REM-on) and REM sleep-inhibiting (REM-off) neuronal populations that act to … Continue reading

Research Article: Role of Corticosterone on Sleep Homeostasis Induced by REM Sleep Deprivation in Rats

Date Published: May 7, 2013 Publisher: Public Library of Science Author(s): Ricardo Borges Machado, Sergio Tufik, Deborah Suchecki, Gianluca Tosini. http://doi.org/10.1371/journal.pone.0063520 Abstract: Sleep is regulated by humoral and homeostatic processes. If on one hand chronic elevation of stress hormones impair sleep, on the other hand, rapid eye movement (REM) sleep deprivation induces elevation of glucocorticoids and … Continue reading

Research Article: Selective REM Sleep Deprivation Improves Expectation-Related Placebo Analgesia

Date Published: December 17, 2015 Publisher: Public Library of Science Author(s): Florian Chouchou, Jean-Marc Chauny, Pierre Rainville, Gilles J. Lavigne, Andrej A. Romanovsky. http://doi.org/10.1371/journal.pone.0144992 Abstract: The placebo effect is a neurobiological and psychophysiological process known to influence perceived pain relief. Optimization of placebo analgesia may contribute to the clinical efficacy and effectiveness of medication for … Continue reading

Research Article: Hypocretin-2 Saporin Lesions of the Ventrolateral Periaquaductal Gray (vlPAG) Increase REM Sleep in Hypocretin Knockout Mice

Date Published: July 22, 2009 Publisher: Public Library of Science Author(s): Satvinder Kaur, Stephen Thankachan, Suraiya Begum, Meng Liu, Carlos Blanco-Centurion, Priyattam J. Shiromani, Kenji Hashimoto. http://doi.org/10.1371/journal.pone.0006346 Abstract: Ten years ago the sleep disorder narcolepsy was linked to the neuropeptide hypocretin (HCRT), also known as orexin. This disorder is characterized by excessive day time sleepiness, inappropriate … Continue reading

Research Article: Brainstem and Spinal Cord Circuitry Regulating REM Sleep and Muscle Atonia

Date Published: October 17, 2011 Publisher: Public Library of Science Author(s): Martina Krenzer, Christelle Anaclet, Ramalingam Vetrivelan, Nishang Wang, Linh Vong, Bradford B. Lowell, Patrick M. Fuller, Jun Lu, Shin Yamazaki. http://doi.org/10.1371/journal.pone.0024998 Abstract: Previous work has suggested, but not demonstrated directly, a critical role for both glutamatergic and GABAergic neurons of the pontine tegmentum in the … Continue reading

Research Article: Brainstem Circuitry Regulating Phasic Activation of Trigeminal Motoneurons during REM Sleep

Date Published: January 20, 2010 Publisher: Public Library of Science Author(s): Christelle Anaclet, Nigel P. Pedersen, Patrick M. Fuller, Jun Lu, Shin Yamazaki. http://doi.org/10.1371/journal.pone.0008788 Abstract: Rapid eye movement sleep (REMS) is characterized by activation of the cortical and hippocampal electroencephalogram (EEG) and atonia of non-respiratory muscles with superimposed phasic activity or twitching, particularly of cranial muscles … Continue reading

Research Article: Role of REM Sleep, Melanin Concentrating Hormone and Orexin/Hypocretin Systems in the Sleep Deprivation Pre-Ischemia

Date Published: January 6, 2017 Publisher: Public Library of Science Author(s): Marta Pace, Antoine Adamantidis, Laura Facchin, Claudio Bassetti, Eric Murillo-Rodriguez. http://doi.org/10.1371/journal.pone.0168430 Abstract: Sleep reduction after stroke is linked to poor recovery in patients. Conversely, a neuroprotective effect is observed in animals subjected to acute sleep deprivation (SD) before ischemia. This neuroprotection is associated with … Continue reading

Research Article: Selective REM-Sleep Deprivation Does Not Diminish Emotional Memory Consolidation in Young Healthy Subjects

Date Published: February 27, 2014 Publisher: Public Library of Science Author(s): Jarste Morgenthaler, Christian D. Wiesner, Karoline Hinze, Lena C. Abels, Alexander Prehn-Kristensen, Robert Göder, Todd W. Troyer. http://doi.org/10.1371/journal.pone.0089849 Abstract: Sleep enhances memory consolidation and it has been hypothesized that rapid eye movement (REM) sleep in particular facilitates the consolidation of emotional memory. The aim … Continue reading

Research Article: Sleep-Related Declarative Memory Consolidation and Verbal Replay during Sleep Talking in Patients with REM Sleep Behavior Disorder

Date Published: December 13, 2013 Publisher: Public Library of Science Author(s): Ginevra Uguccioni, Olivier Pallanca, Jean-Louis Golmard, Pauline Dodet, Bastien Herlin, Smaranda Leu-Semenescu, Isabelle Arnulf, Friedemann Paul. http://doi.org/10.1371/journal.pone.0083352 Abstract: To determine if sleep talkers with REM sleep behavior disorder (RBD) would utter during REM sleep sentences learned before sleep, and to evaluate their verbal memory … Continue reading

Research Article: Selective Coupling between Theta Phase and Neocortical Fast Gamma Oscillations during REM-Sleep in Mice

Date Published: December 5, 2011 Publisher: Public Library of Science Author(s): Claudia Scheffzük, Valeriy I. Kukushka, Alexei L. Vyssotski, Andreas Draguhn, Adriano B. L. Tort, Jurij Brankačk, Fabien Tell. http://doi.org/10.1371/journal.pone.0028489 Abstract: The mammalian brain expresses a wide range of state-dependent network oscillations which vary in frequency and spatial extension. Such rhythms can entrain multiple neurons into … Continue reading