renal cortex | definition

  • outer part of kidney containing all of the nephrons
  • some nephrons have loops of Henle extending into the medulla


Betts, J. G., Young, K. A., Wise, J. A., Johnson, E., Poe, B., Kruse, D. H., … DeSaix, P. (n.d.). Anatomy and Physiology. Houston, Texas: OpenStax. Access for free at:

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Research Article: The Expression of EPOR in Renal Cortex during Postnatal Development

Date Published: July 26, 2012 Publisher: Public Library of Science Author(s): Lu Xiao, Zhanyong Li, Pengjuan Xu, Zhigui Li, Jing Xu, Zhuo Yang, Giorgio F. Gilestro. Abstract Erythropoietin (EPO), known for its role in erythroid differentiation, has been shown to be an important growth factor for brain and heart. EPO is synthesized by fibroblast-like cells … Continue reading

Research Article: Expression of TRPC6 in Renal Cortex and Hippocampus of Mouse during Postnatal Development

Date Published: June 6, 2012 Publisher: Public Library of Science Author(s): Pengjuan Xu, Jing Xu, Zhigui Li, Zhuo Yang, Nick Ashton. Abstract TRPC6, a member of the TRPC family, attracts much attention from the public because of its relationship with the disease. In both the brain and kidney, TRPC6 serves a variety of functions. The … Continue reading

Research Article: Transcriptome signature for dietary fructose-specific changes in rat renal cortex: A quantitative approach to physiological relevance

Date Published: August 1, 2018 Publisher: Public Library of Science Author(s): Agustin Gonzalez-Vicente, Jeffrey L. Garvin, Ulrich Hopfer, Ines Armando. Abstract Fructose consumption causes metabolic diseases and renal injury primarily in the renal cortex where fructose is metabolized. Analyzing gene differential expression induced by dietary manipulation is challenging. The effects may depend on the … Continue reading

Research Article: Experimental autoimmune encephalomyelitis (EAE) up-regulates the mitochondrial activity and manganese superoxide dismutase (MnSOD) in the mouse renal cortex

Date Published: April 24, 2018 Publisher: Public Library of Science Author(s): Balamurugan Packialakshmi, Xiaoming Zhou, Rodrigo Franco. Abstract Increases of the activity of mitochondrial electron transport chain generally lead to increases of production of ATP and reactive oxygen species (ROS) as by-products. MnSOD is the first line of defense against the stress induced by … Continue reading


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