Date Published: July 01, 2011
Publisher: International Union of Crystallography
Author(s): Lei Liu, Tao Song, Liang-zhong Xu.
In the title compound, C14H11F2N3S, the heterocyclic five-membered ring has an envelope conformation. Although the molecule is chiral, the compound is a racemate (R/S). There is a weak intermolecular C—H⋯π interaction but no classical hydrogen bonds are observed in the crystal structure.
For the biological activity of thiazoles and thiazolidines, see: Melnikov et al. (1979 ▶); Kratt et al. (1986 ▶). For the synthesis, see: Hense et al. (2002 ▶). For a related structure, see: Xu et al. (2005 ▶). For puckering parameters, see: Cremer & Pople (1975 ▶).