Research Article: 1-(2-Chloro­eth­yl)-1H-pyrazolo­[3,4-d]pyrimidin-4(5H)-one

Date Published: July 01, 2012

Publisher: International Union of Crystallography

Author(s): Mohammed Iqbal A. Khazi, Nikhath Fathima, Ningaraddi S. Belavagi, Noor Shahina Begum, I. M. Khazi.

http://doi.org/10.1107/S1600536812025184

Abstract

In the title compound, C7H7ClN4O, the pyrazolo­pyrimidine ring is essentially planar, the r.m.s. deviation of the fitted atoms being 0.0071 Å. The crystal structure features strong N—H⋯O hydrogen bonds and further consolidated by weak C—H⋯O, C—H⋯N and C—H⋯Cl inter­actions.

Partial Text

For the biological activity of pyrazolo­pyrimidines, see: Carraro et al. (2006 ▶). For a related structure, see: Dolzhenko et al. (2009 ▶). For the graph-set analysis of hydrogen bonding, see: Bernstein et al. (1995 ▶).

Source:

http://doi.org/10.1107/S1600536812025184