Research Article: 1-(2-Hy­droxy-4-meth­oxy­phen­yl)-3-(4-methyl­phen­yl)prop-2-en-1-one

Date Published: April 01, 2011

Publisher: International Union of Crystallography

Author(s): G. B. Thippeswamy, D. Vijay Kumar, B. S. Jayashree, M. A. Sridhar, J. Shashidhara Prasad.


The mol­ecule of the title compound, C17H16O3, exists in the E conformation with respect to the central C=C bond, is almost planar(r.m.s. deviation = 0.003 Å) and has an intra­molecular O—H⋯O hydrogen bond, which generates an S(6) ring. In the crystal, mol­ecules are linked by C—H⋯O inter­actions.

Partial Text

For the biological activity of compounds with a chalcone backbone, see: Jayashree et al. (2009 ▶); Epifano et al. (2007 ▶); Onyilagna et al. (1997 ▶); Satyanarayana et al. (2004 ▶); Deshpande et al. (1999 ▶); Hsieh et al. (2000 ▶); Khatib et al. (2005 ▶); Barford et al. (2002 ▶); Nielsen et al. (1995 ▶); Severi et al. (1998 ▶); Siva Kumar et al. (2007 ▶). For a related structure, see: Thippeswamy et al. (2010 ▶). For puckering parameters, see: Cremer & Pople (1975 ▶).




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