Date Published: July 01, 2011
Publisher: International Union of Crystallography
Author(s): Bohari M. Yamin, Ruhana L. Lawi, Halima F. Salem.
In the title compound, C13H15FN2S, the dihydropyrimidine ring is essentially planar, with a maximum deviation of 0.086 (3) Å from the mean plane of the rest of the ring for the dimethylated C atom. The benzene ring is almost perpendicular to the dihydropyrimidine ring, with a dihedral angle of 83.97 (14)°. The crystal packing is characterized by centrosymmetric dimers resulting from pairs of intermolecular N—H⋯S hydrogen bonds. There are also C—H⋯π interactions.
For the biological properties of related compounds, see: Rovnyak et al. (1995 ▶); Kappe (2000 ▶); Alam et al. (2005 ▶); Sriram et al. (2006 ▶); Leite et al. (2006 ▶). For related structures, see: Yamin et al. (2005 ▶); Ismail et al. (2007 ▶); Saeed et al. (2010 ▶); Yamin & Salem (2011 ▶). For standard bond lengths, see: Allen et al. (1987 ▶).