Research Article: 1-(3-Fluoro­phen­yl)-4,4,6-trimethyl-3,4-dihydro­pyrimidine-2(1H)-thione

Date Published: July 01, 2011

Publisher: International Union of Crystallography

Author(s): Bohari M. Yamin, Ruhana L. Lawi, Halima F. Salem.

http://doi.org/10.1107/S1600536811023671

Abstract

In the title compound, C13H15FN2S, the dihydro­pyrimidine ring is essentially planar, with a maximum deviation of 0.086 (3) Å from the mean plane of the rest of the ring for the dimethyl­ated C atom. The benzene ring is almost perpendicular to the dihydro­pyrimidine ring, with a dihedral angle of 83.97 (14)°. The crystal packing is characterized by centrosymmetric dimers resulting from pairs of inter­molecular N—H⋯S hydrogen bonds. There are also C—H⋯π inter­actions.

Partial Text

For the biological properties of related compounds, see: Rovnyak et al. (1995 ▶); Kappe (2000 ▶); Alam et al. (2005 ▶); Sriram et al. (2006 ▶); Leite et al. (2006 ▶). For related structures, see: Yamin et al. (2005 ▶); Ismail et al. (2007 ▶); Saeed et al. (2010 ▶); Yamin & Salem (2011 ▶). For standard bond lengths, see: Allen et al. (1987 ▶).

Source:

http://doi.org/10.1107/S1600536811023671