Research Article: 1-(3,5-Dimeth­oxy­benz­yl)-1H-pyrrole

Date Published: May 01, 2012

Publisher: International Union of Crystallography

Author(s): Yueqing Li, Xu Zhang, Shiyong Huo, Wei Huang, Weijie Zhao.


The title compound, C13H15NO2, was synthesized from 3,5-dimeth­oxy­benzaldehyde. The dihedral angle between the pyrrole and benzene rings is 89.91 (5)°. In the crystal, weak C—H⋯O and C—H⋯π interactions link the mol­ecules into a three-dimensional network.

Partial Text

For the anti-HIV-1 activity of N-(aryl­meth­yl)-pyrrole, see: Liu et al. (2008 ▶); Teixeira et al. (2008 ▶). For a related structure, see: Wang et al. (2011 ▶). For the synthesis of 3,5-dimeth­oxy-benzyl­amine, see: Yraola et al. (2006 ▶).