Date Published: February 01, 2012
Publisher: International Union of Crystallography
Author(s): S. Rosepriya, A. Thiruvalluvar, K. Saravanan, J. Jayabharathi, Ray J. Butcher.
In the title compound, C19H19FN2O2, the imidazole ring is essentially planar [maximum deviation = 0.0030 (8) Å] and makes dihedral angles of 66.45 (7) and 29.98 (7)° with the benzene rings attached to the ring N and C atoms, respectively. The dihedral angle between the two benzene rings is 64.79 (7)°. A C—H⋯π interaction is found in the crystal structure. The two methoxy groups were found to be disordered over two sets of sites with occupancy factors of 0.803 (4) and 0.197 (4). The F atom is disordered over two sites with occupancy factors of 0.929 (4) and 0.071 (4).
For general background to the use of imidazole derivatives as drugs, see: Dooley et al. (1992 ▶); Jackson et al. (2000 ▶); Banfi et al. (2006 ▶). For a related structure and applications of imidazole derivatives, see: Rosepriya et al. (2011 ▶).