Research Article: 1-[(4-Bromo­phen­yl)(morpholin-4-yl)meth­yl]naphthalen-2-ol

Date Published: February 01, 2012

Publisher: International Union of Crystallography

Author(s): Qun Zhao.


The title compound, C21H20BrNO2, was obtained from a condensation reaction of 4-bromo­benzaldehyde, 2-naphthol and morpholine. The mol­ecular conformation is stabilized by an intra­molecular O—H⋯N hydrogen bond, closing a six-membered ring. The dihedral angle between the naphthalene ring system and the benzene ring is 76.72 (8)°. In addition to the intra­molecular hydrogen bond, the O—H groups of centrosymmetrically related mol­ecules form short inter­molecular H⋯O contacts of 2.59 Å. These mol­ecules are also linked by pairs of C—H⋯O inter­actions, generating an R22(14) motif.

Partial Text

For applications of Betti-type reactions, see: Lu et al. (2002 ▶); Xu et al. (2004 ▶); Wang et al. (2005 ▶).