Date Published: March 01, 2012
Publisher: International Union of Crystallography
Author(s): Sheng-Hai Guo, Ji-Liang Wang, Dong-Qiang Guo, Xin-Ying Zhang.
The title compound, C12H13ClN2O2, crystallizes with two independent but very similar molecules (A and B) in the asymmetric unit. The pyrazole ring in each molecule has an envelope conformation. The dihedral angle between the pyrazole ring mean plane and the benzene ring is 86.07 (14)° in A and 85.99 (14)° in B. In the crystal, the A and B molecules are linked via a pair of O—H⋯O hydrogen bonds, forming dimers. These dimers are further linked via C—H⋯O interactions to form –A–B–A–B– chains propagating along the c-axis direction.
For the bioactivities of 5-hydroxypyrazolines, see: Sauzem et al. (2008 ▶); Zhao et al. (2009 ▶); Idrees et al. (2009 ▶). For the crystal structures of related 5-hydroxypyrazolines, see: Kargar, Kia, Froozandeh et al. (2011 ▶); Kargar, Kia, Moghadamm et al. (2011 ▶).