Research Article: 1-Acetyl-4-(phenyl­sulfan­yl)imidazolidin-2-one

Date Published: March 01, 2012

Publisher: International Union of Crystallography

Author(s): Alaa A.-M. Abdel-Aziz, Adel S. El-Azab, Amer M. Alanazi, Seik Weng Ng, Edward R. T. Tiekink.


The five-membered ring in the title imidazolidinone derivative, C11H12N2O2S, adopts an envelope conformation with the S-bound C atom being the flap atom. Overall, the mol­ecule has a U-shaped conformation as both rings are folded towards each other [dihedral angle = 31.66 (6)°]. An eight-membered amide {⋯HNCO}2 synthon leads to hydrogen-bonded dimeric aggregates in the crystal: these are additionally linked by C—H⋯π inter­actions.

Partial Text

For the anti­tumour potential of imidazolidinones, see: Abdel-Aziz et al. (2012 ▶). For ring conformational analysis, see: Cremer & Pople (1975 ▶).