Research Article: 1-Benzyl-3-[(4-methyl­phen­yl)imino]­indolin-2-one

Date Published: July 01, 2012

Publisher: International Union of Crystallography

Author(s): Adebomi A. Ikotun, Pius O. Adelani, Gabriel O. Egharevba.

http://doi.org/10.1107/S1600536812024506

Abstract

In the title compound, C22H18N2O, the phenyl and tolyl rings make dihedral angles of 84.71 (7) and 65.11 (6)°, respectively, with the isatin group. The aromatic rings make a dihedral angle of 60.90 (8)°. The imino C=N double bond, exists in an E conformation. In the crystal, mol­ecules are linked by weak π–π stacking inter­actions [centroid–centroid distance = 3.6598 (13) Å].

Partial Text

For background to isatin, its derivatives and their biological significance, see: Chazeau et al. (1992 ▶); Igosheva et al. (2004 ▶); Medvedev et al. (1996 ▶); Abele et al. (2003 ▶). For metal complexes of isatin derivatives and their biological significance, see: Rodriguez-Arguelles et al. (2004 ▶); Singh et al. (2005 ▶); Chohan et al. (2006 ▶); Adetoye et al. (2009 ▶); Ikotun et al. (2012 ▶). For N-benzyl isatin, its derivatives and biological significance, see Akkurt et al. (2006 ▶); Jarrahpour & Khalili (2007 ▶); Cao et al. (2009 ▶).

Source:

http://doi.org/10.1107/S1600536812024506