Research Article: 1-[(Cyclo­propyl­meth­oxy)meth­yl]-5-ethyl-6-(4-methyl­benzyl)-1,2,3,4-tetra­hydro­pyrimidine-2,4-dione

Date Published: February 01, 2012

Publisher: International Union of Crystallography

Author(s): Nasser R. El-Brollosy, Ali A. El-Emam, Omar A. Al-Deeb, Seik Weng Ng.

http://doi.org/10.1107/S1600536811055681

Abstract

The pyrimidine ring in the title compound, C19H24N2O3, is nearly planar (r.m.s. deviation = 0.008 Å); the C atom at the 5-position deviates by 0.054 (3) Å from the mean plane and the C atom at the 6-position by 0.006 (3) Å in the opposite direction. The benzene ring is approximately perpendicular to the pyrimidine ring [dihedral angle = 83.90 (10)°]. The amino group is hydrogen-bond donor to the exocyclic O atom at the 2-position of an adjacent mol­ecule, the hydrogen bond generating an inversion dimer. The cyclo­propyl ring is disordered over two sets of sites with the major component having 71.5 (4)% occupancy.

Partial Text

For the synthesis, see: El-Brollosy et al. (2009 ▶).

 

Source:

http://doi.org/10.1107/S1600536811055681