Research Article: 1-Formyl-c-3,t-3-dimethyl-r-2,c-6-di­phenyl­piperidin-4-one

Date Published: March 01, 2012

Publisher: International Union of Crystallography

Author(s): K. Ravichandran, P. Sakthivel, P. Ramesh, S. Ponnuswamy, M. N. Ponnuswamy.


In the title compound, C20H21NO2, the piperidine ring adopts a distorted boat conformation. The phenyl rings substituted at the 2- and 6-positions of the piperidine ring subtend angles of 86.0 (1) and 67.3 (1)° with the mean plane of the piperidine ring (all six non-H atoms). The crystal packing features C—H⋯O inter­actions.

Partial Text

For the biological activity of piperidine derivatives, see: Aridoss et al. (2009 ▶); Nalanishi et al. (1974 ▶); Michael (2001 ▶); Pinder (1992 ▶); Rubiralta et al. (1991 ▶). For puckering parameters, see: Cremer & Pople (1975 ▶). For asymmetry parameters, see: Nardelli (1983 ▶). For hydrogen-bond motifs, see: Bernstein et al.(1995 ▶).