Research Article: 10,16-Dichloro-6,20-dioxa-3,23-diaza­tetra­cyclo­[,12.014,19]nona­cosa-1(29),7,9,11,14(19),15,17,25,27-nona­ene-4,22-dione methanol monosolvate

Date Published: March 01, 2012

Publisher: International Union of Crystallography

Author(s): Michaela Pojarová, Michal Dušek, Zdeňka Sedláková, Emanuel Makrlík.


In the title compound, C25H22Cl2N2O4·CH3OH, the macrocyclic mol­ecule adopts a slightly distorted C2-symmetric conformation. The macrocyclic mol­ecules are linked via N—H⋯O hydrogen bonds between the amide groups into chains extending along the [010] direction. The methanol mol­ecules bridge these chains via N—H⋯O and O—H⋯O hydrogen bonds with the formation of a two-dimensional polymeric structure parallel to (001). The methanol mol­ecule is disordered over two positions with the occupancy ratio of 9:1. The disorder of the solvent molecule is caused by weak intermolecular C—H⋯Cl hydrogen bonding.

Partial Text

For application of macrocycles, see: Hayvali & Hayvali (2005 ▶); Kleinpeter et al. (1997 ▶); Jaiyu et al. (2007 ▶); Christensen et al. (1997 ▶); Alexander (1995 ▶). For the synthetic procedure, see: Ertul et al. (2009 ▶).