Research Article: 10a-Hy­droxy-9-(4-meth­oxy­phen­yl)-3,4,5,6,7,8a,9,10a-octa­hydro-1H-xanthene-1,8(2H)-dione

Date Published: August 01, 2012

Publisher: International Union of Crystallography

Author(s): Hoong-Kun Fun, Chin Wei Ooi, B. Palakshi Reddy, V. Vijayakumar, S. Sarveswari.


In the title compound, C20H22O5, the tetra­hydro­pyran, cyclo­hexene and cyclo­hexane rings of the xanthene ring system adopt half-chair, half-boat and chair conformations, respectively. The mean plane of the four roughly planar atoms of the tetra­hydro­pyran ring (r.m.s. deviation = 0.111 Å) forms a dihedral angle of 82.91 (4)° with the meth­oxy­benzene group. In the crystal, mol­ecules are linked via O—H⋯O and C—H⋯O hydrogen bonds into sheets lying parallel to the ac plane. The crystal is further consolidated by weak C—H⋯π inter­actions.

Partial Text

For background to the applications of xanthene, see: Menchen et al. (2003 ▶); Knight & Stephens (1989 ▶). For our previous studies in this area, see: Palakshi Reddy et al. (2010 ▶); Reddy et al. (2009 ▶). For ring conformations, see: Cremer & Pople (1975 ▶). For a related structure, see: Loh et al. (2011 ▶). For bond length data, see: Allen et al. (1987 ▶). For the stability of the temperature controller used for data collection, see: Cosier & Glazer (1986 ▶).




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