Research Article: (1RS,2SR,5SR)-9-Benzyl-2-[(1RS)-1-hy­droxy­benz­yl]-9-aza­bicyclo­[3.3.1]nonan-3-one from synchrotron data

Date Published: May 01, 2012

Publisher: International Union of Crystallography

Author(s): Ryszard Lazny, Karol Wolosewicz, Zbigniew Dauter, Krzysztof Brzezinski.

http://doi.org/10.1107/S1600536812014754

Abstract

In the crystal structure of the racemic title compound, C22H25NO2, solved and refined against sychrotron diffraction data, the hy­droxy group and the carbonyl O atom participate in the formation of O—H⋯O hydrogen bonds between pairs of enanti­omers related by a crystallographic centre of symmetry.

Partial Text

For recent background literature on the synthesis, structure and applications of related granatane-derived aldols, see: Lazny et al. (2011a ▶) and references cited therein. For the stereoselective syntheses, applications and structures of related tropinone aldols, see: Sienkiewicz et al. (2009 ▶); Lazny et al. (2011b ▶); Brzezinski et al. (2012 ▶) and for related nortropin­one aldols, see: Lazny et al. (2001 ▶, 2010 ▶); Lazny & Nodzewska (2003 ▶).

 

Source:

http://doi.org/10.1107/S1600536812014754