Research Article: 2-[1,1-Dioxo-2-(2,4,5-trifluoro­benz­yl)-2H-1,2-benzothia­zin-4-yl]acetic acid

Date Published: May 01, 2012

Publisher: International Union of Crystallography

Author(s): Yanchun Yang, Youzhu Yu, Changjin Zhu.


In the title compound, C17H12F3NO4S, the heterocyclic thia­zine ring adopts a half-chair conformation with the S and the N atoms displaced by −0.608 (3) and 0.105 (3) Å, respectively, from the mean plane formed by the remaining ring atoms. The dihedral angle between the two benzene rings is 36.63 (8)° and the acetic acid group is inclined at right angles [89.78 (8) °] to the mean plane formed by the C atoms of the thia­zine ring. The crystal structure features O—H⋯O and C—H⋯O hydrogen bonds.

Partial Text

For pharmaceuticals properties of benzothia­zines, see: Zia-ur-Rehman et al. (2006 ▶). For synthetic details of the title compound, see: Chen et al. (2011 ▶). For related structures, see: Ahmad et al. (2008 ▶); Zia-ur-Rehman et al. (2008 ▶).