Research Article: 2-[(2-Acet­oxy­benzo­yl)­oxy]benzoic acid

Date Published: July 01, 2012

Publisher: International Union of Crystallography

Author(s): Katarzyna A. Solanko, Andrew D. Bond.

http://doi.org/10.1107/S1600536812026475

Abstract

The title compound, C16H12O6, is a common impurity of ortho-acetyl­salicylic acid (aspirin). The benzene rings form a dihedral angle of 81.9 (1)° while the acetyl and carboxyl groups form dihedral angles of 74.0 (1) and 26.4 (2)°, respectively, with the benzene rings to which they are bound. In the crystal, mol­ecules are linked by pairs of O—H⋯O hydrogen bonds between the carboxyl groups, forming inversion dimers.

Partial Text

For background literature concerning the crystallization and crystal structure of aspirin, see: Bond et al. (2007 ▶, 2011 ▶). For a discussion of the pharmacological effects of acetyl­salicyl­salicylic acid, see: Bundgaard (1974 ▶). For related structures, see: Greener et al. (2000 ▶); Cox et al. (2000 ▶); Iqbal et al. (2007 ▶).

 

Source:

http://doi.org/10.1107/S1600536812026475

 

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