Date Published: June 01, 2012
Publisher: International Union of Crystallography
Author(s): Gang Liu, Jie Gao.
The title compound, C9H12N2O3, was synthesized by the reaction of ethyl 2-(4-methoxyphenoxy)acetate with hydrazine hydrate in ethanol. In the acetohydrazide group, the N—N bond is relatively short [1.413 (2) Å], suggesting some degree of electronic delocalization in the molecule. In the crystal, molecules are linked into sheets lying parallel to the ab plane by N—H⋯N and N—H⋯O hydrogen bonds.
For general background to and the biological activity of hydrazides, see: Khattab (2005 ▶); Ozdemir et al. (2009 ▶); Ashiq et al. (2009 ▶); Zhang & Shi (2009 ▶). For related structures, see: Dutkiewicz et al. (2009 ▶); Fun et al. (2009 ▶, 2010a ▶,b ▶, 2011 ▶).