Research Article: 2-Amino-4-(2-chloro­phen­yl)-6-(naph­thalen-1-yl)pyridine-3-carbonitrile

Date Published: June 01, 2012

Publisher: International Union of Crystallography

Author(s): Hong-Xia Wei, Jing Zhu, Ming Li, Jian-qiang Wang, Cheng Guo.


In the title compound, C22H14ClN3, prepared by a one-pot reaction under microwave irradiation, the dihedral angles between the central pyridine ring and the pendant naphthyl and chloro­benzene ring systems are 49.2 (2) and 58.2 (3)°, respectively. In the crystal, inversion dimers linked by pairs of N—H⋯N hydrogen bonds generate R22(8) loops. The pyridine N atom is the acceptor.

Partial Text

For the use of 2-amino-3-cyano­pyridines as inter­mediates in the preparation of heterocyclic compounds, see: Shishoo et al. (1983 ▶). For the synthesis, see: Mantri et al. (2008 ▶). For related structures, see: Mkhalid et al. (2006 ▶).




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