Research Article: (2-Methyl-3-nitro­phen­yl)methanol

Date Published: August 01, 2009

Publisher: International Union of Crystallography

Author(s): Jian-hong Zhang, You-sheng Chen, Xi Wang.


The asymmetric unit of the title compound, C8H9NO3, contains two crystallographically independent mol­ecules, whose aromatic rings are oriented at a dihedral angle of 83.29 (3)°. In the crystal structure, inter­molecular O—H⋯O hydrogen bonds link the mol­ecules into chains.

Partial Text

The title compound is an intermediate in the synthesis of the monomer 2-methyl-3-nitrobenzaldehyde, utilized to synthesize ergoline derivatives which have potential use in the treatment of Parkinson’s disease, see: Kozikowski et al. (1980 ▶). For a related structure, see: Wu et al. (1994 ▶). For bond-length data, see: Allen et al. (1987 ▶).




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