Research Article: 2-(N-Cyclo­hexyl­carbamo­yl)benzene­sulfonamide

Date Published: February 01, 2012

Publisher: International Union of Crystallography

Author(s): Waseeq Ahmad Siddiqui, Adnan Ashraf, Hamid Latif Siddiqui, Muhammad Akram, Masood Parvez.


The asymmetric unit of the title compound, C13H18N2O3S, contains two mol­ecules with similar conformations. In both mol­ecules, the cyclo­hexyl rings adopt chair conformations, with the attached N atom in an equatorial orientation and an intra­molecular N—H⋯O hydrogen bond generates an S(7) ring. In the crystal, N—H⋯O hydrogen bonds link the mol­ecules and a C—H⋯O hydrogen bond is also observed. The crystal studied was a racemic twin.

Partial Text

For the biological activity of benzene­sulfonamide derivatives, see: Petrov et al. (2006 ▶); Eatedal et al. (2002 ▶); Ahmad et al. (2010 ▶). For related structures, see: Siddiqui et al. (2007 ▶, 2008 ▶). For ring puckering parameters, see: Cremer & Pople (1975 ▶).