Research Article: 21-(3-Carboxy­propano­yl)-11β,17-dihydroxy­pregn-4-ene-3,20-dione monohydrate

Date Published: June 01, 2010

Publisher: International Union of Crystallography

Author(s): Hongliang Wang, Junhai Xiao, Pengfei Chen, Tie-Min Sun.

http://doi.org/10.1107/S160053681001648X

Abstract

In the title compound, C25H34O8·H2O, the two crylohexane rings adopt chair conformations. In the crystal, the organic mol­ecule and the water mol­ecule are linked by O—H⋯O hydrogen bonds, generating a three-dimensional network.

Partial Text

For background to glucocorticoids, see: Schäcke et al. (2002 ▶). For the synthesis, see: Fang et al. (2007 ▶).

Source:

http://doi.org/10.1107/S160053681001648X