Research Article: 2,4,6,8-Tetra­kis(4-chloro­phen­yl)-3,7-diaza­bicyclo­[3.3.1]nonan-9-one O-benzyl­oxime acetone monosolvate

Date Published: May 01, 2012

Publisher: International Union of Crystallography

Author(s): Dong Ho Park, V. Ramkumar, P. Parthiban.

http://doi.org/10.1107/S1600536812016509

Abstract

In the title compound, C38H31Cl4N3O·C3H6O, the 3,7-diaza-bicycle exists in a chair–boat conformation. The 4-chloro­phenyl groups attached to the chair form are equatorially oriented at an angle of 18.15 (3)° with respect to each other, whereas the 4-chloro­phenyl groups attached to the boat form are oriented at an angle of 32.64 (3)°. In the crystal, mol­ecules are linked by N—H⋯π and C—H⋯O inter­actions.

Partial Text

For the synthesis and stereochemistry of 3,7-diaza­bicyclo­[3.3.1]nonan-9-one derivatives, see: Parthiban et al. (2008 ▶). For the biological activity of 3,7-diaza­bicyclo­[3.3.1]nonan-9-one derivatives and related structures, see: Parthiban et al. (2009 ▶, 2010 ▶); Asakawa (1995 ▶); Jayaraman & Avila (1981 ▶). For ring puckering parameters, see: Cremer & Pople (1975 ▶); Nardelli (1983 ▶); Luger & Bülow (1983 ▶).

 

Source:

http://doi.org/10.1107/S1600536812016509