Research Article: (2S,4S)-2-[(S,E)-2-Bromo-1-nitro­methyl-3-phenyl­all­yl]-4-methyl­cyclo­hexa­none

Date Published: April 01, 2012

Publisher: International Union of Crystallography

Author(s): Long Zhao, Chao Wu, Wen-Zeng Weng, Chu-Xia Yan, Ai-Bao Xia.


The crystal structure of the title compoud, C17H20BrNO3, contains three chiral centers, which all exhibit an S configuration. The C=C double bond has an E conformation. The cyclo­hexane ring is in a chair conformation. In the crystal, mol­ecules are linked by weak N—O⋯Br inter­actions [O⋯Br = 3.136 (4) Å].

Partial Text

For related compounds, see: Li et al. (2009 ▶); Wu et al. (2011 ▶). For the asymmetric Michael reaction, which allows for the formation of three contiguous asymmetric centers, see: Agarwal & Peddinti (2011 ▶); Lu et al. (2010 ▶); Luo et al. (2007 ▶).