Research Article: 3β-Chloro-6-[2-(2-cyano­acet­yl)hydrazin-1-yl­idene]-5α-cholestane

Date Published: April 01, 2012

Publisher: International Union of Crystallography

Author(s): Samina Khan Yusufzai, Hasnah Osman, Aisyah Saad Abdul Rahim, Suhana Arshad, Ibrahim Abdul Razak.


The asymmetric unit of the title compound, C30H48ClN3O, contains two mol­ecules, A and B. In both mol­ecules, the three cyclo­hexane rings in the steroid fused ring systems adopt chair conformations, while the cyclo­pentane rings adopt envelope and twist conformations in mol­ecules A and B, respectively. In mol­ecule B, the cyano group is disordered over two orientations with refined site-occupancies of 0.593 (8) and 0.407 (8). An intra­molecular C—H⋯N inter­action forms an S(10) ring in both mol­ecules. In the crystal, mol­ecules are linked by N—H⋯O, C—H⋯O and C—H⋯N inter­actions, resulting is chains propagating along the a-axis direction.

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For related structures, see: Yusufzai et al. (2012 ▶); Ketuly et al. (2011 ▶). For ring conformations, see: Cremer & Pople (1975 ▶). For hydrogen-bond motifs, see: Bernstein et al. (1995 ▶). For the stability of the temperature controller used in the data collection, see: Cosier & Glazer (1986 ▶).