Date Published: May 01, 2009
Publisher: International Union of Crystallography
Author(s): Hefang Shi, Yingxia Li.
The title compound, C21H34O4, is a steriod of the pregnane family prepared by the sequential oxidation and reduction of 3β,12β-diacetoxy-20-ethylenedioxypregnan-14-ene. The conformations of the six-membered rings are close to chair forms, while the five-membered ring adopts an envelope conformation. All the rings are trans-fused and an intramolecular O—H⋯O hydrogen bond occurs. In the crystal structure, intermolecular O—H⋯O hydrogen bonds link the molecules into a two-dimensional network.
For the synthesis, see: Templeton & Yan (1992 ▶); Fell & Heathcock (2002 ▶). For background on hecogenin, see: Ranu & Samanta (2003 ▶).