Research Article: 3′-(3-Hy­droxy­phen­yl)-4-methyl­spiro­[benzo[e][1,4]diazepine-3,2′-oxirane]-2,5(1H,4H)-dione

Date Published: July 01, 2011

Publisher: International Union of Crystallography

Author(s): Jun-Liang Liu, Zhi-Yu Hu, Qing-Yan Xu.

http://doi.org/10.1107/S1600536811022161

Abstract

In the title compound, C17H14N2O4, the seven-membered ring adopts a boat conformation, and the two benzene rings make a dihedral angle of 45.22 (5)°. The crystal packing is stabilized by inter­molecular N—H⋯O and O—H⋯O hydrogen bonds.

Partial Text

For the biological activity of the title compound, see: Birkinshaw et al. (1963 ▶); Cutler et al. (1984 ▶); Heguy, et al. (1998 ▶). For the biosynthesis of cyclo­penol, see: Nover & Luckner (1969 ▶).

 

Source:

http://doi.org/10.1107/S1600536811022161

 

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