Research Article: 3-(4-Bromo­phenyl­sulfon­yl)-8-methyl-1,3-diaza­spiro­[4.5]decane-2,4-dione

Date Published: August 01, 2009

Publisher: International Union of Crystallography

Author(s): M. Kalim Kashif, M. Khawar Rauf, Michael Bolte, Shahid Hameed.

http://doi.org/10.1107/S1600536809027305

Abstract

The crystal structure of the title compound, C15H17BrN2O4S, is stabilized by inter­molecular N—H⋯O hydrogen bonds which link the mol­ecules into centrosymmetric dimers. The dihedral angle subtended by the 4-bromo­phenyl group with the mean plane passing through the hydantoin unit is 83.29 (5)°. The cyclo­hexyl group adopts an ideal chair conformation with the methyl group in an equatorial position.

Partial Text

For background to diabetes and its treatment, see: Tiwari & Rao (2002 ▶); DeFronzo (1999 ▶); Feinglos & Bethel (1998 ▶); Murakami et al., (1997 ▶); Kashif, Ahmad et al. (2008 ▶). For related structures, see: Gauthier et al. (1997 ▶); Hussain et al. (2009a ▶,b ▶); Kashif, Hussain et al. (2008 ▶).

 

Source:

http://doi.org/10.1107/S1600536809027305

 

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