Date Published: August 01, 2009
Publisher: International Union of Crystallography
Author(s): M. Kalim Kashif, M. Khawar Rauf, Michael Bolte, Shahid Hameed.
The crystal structure of the title compound, C15H17BrN2O4S, is stabilized by intermolecular N—H⋯O hydrogen bonds which link the molecules into centrosymmetric dimers. The dihedral angle subtended by the 4-bromophenyl group with the mean plane passing through the hydantoin unit is 83.29 (5)°. The cyclohexyl group adopts an ideal chair conformation with the methyl group in an equatorial position.
For background to diabetes and its treatment, see: Tiwari & Rao (2002 ▶); DeFronzo (1999 ▶); Feinglos & Bethel (1998 ▶); Murakami et al., (1997 ▶); Kashif, Ahmad et al. (2008 ▶). For related structures, see: Gauthier et al. (1997 ▶); Hussain et al. (2009a ▶,b ▶); Kashif, Hussain et al. (2008 ▶).