Research Article: 3-Acetyl-5-phenyl-1-p-tolyl-1H-pyrazole-4-carbonitrile

Date Published: April 01, 2012

Publisher: International Union of Crystallography

Author(s): Hatem A. Abdel-Aziz, Hazem A. Ghabbour, Suchada Chantrapromma, Hoong-Kun Fun.

http://doi.org/10.1107/S1600536812011762

Abstract

In the title pyrazole derivative, C19H15N3O, the central pyrazole ring makes dihedral angles of 42.71 (9) and 61.34 (9)°, respectively, with the phenyl and p-tolyl rings. The dihedral angle between the phenyl and p-tolyl rings is 58.22 (9)°. The 3-acetyl-1H-pyrazole-4-carbonitrile unit is essentially planar, with an r.m.s. deviation of 0.0295 (1) Å for the ten non-H atoms.

Partial Text

For bond-length data, see: Allen et al. (1987 ▶). For background to and the bioactivity of pyrazole derivatives, see: Abdel-Aziz et al. (2009 ▶, 2010 ▶); Abdel-Wahab et al. (2009 ▶); Dawood et al. (2003 ▶). For a related structure, see: Abdel-Aziz et al. (2012 ▶).

 

Source:

http://doi.org/10.1107/S1600536812011762