Research Article: 3-(Adamantan-1-yl)-4-ethyl-1-[(4-phenyl­piperazin-1-yl)meth­yl]-1H-1,2,4-triazole-5(4H)-thione

Date Published: August 01, 2012

Publisher: International Union of Crystallography

Author(s): Ali A. El-Emam, Ebtehal S. Al-Abdullah, Hanaa M. Al-Tuwaijri, Mohammed Said-Abdelbaky, Santiago García-Granda.

http://doi.org/10.1107/S160053681202990X

Abstract

The title compound, C25H35N5S, has an approximately C-shaped conformation. The dihedral angle between the triazole and phenyl planes is 79.5 (2)°. The crystal structure consists of infinite chains parallel to the b axis, constructed by C—H⋯S hydrogen bonds between translation-related mol­ecules. Adjacent chains are linked via weak C—H⋯C inter­actions between the adamantyl and phenyl groups.

Partial Text

For the biological activity of adamantane derivatives and adamantyl-1,2,4-triazoles, see: Vernier et al. (1969 ▶); Al-Deeb et al. (2006 ▶); Al-Omar et al. (2010 ▶); El-Emam & Ibrahim (1991 ▶); El-Emam et al. (2004 ▶); Kadi et al. (2007 ▶, 2010 ▶). For related adamantyl-1,2,4-triazole structures, see: Al-Tamimi et al. (2010 ▶); Al-Abdullah et al. (2012 ▶); El-Emam et al. (2012 ▶); Lahsasni et al. (2012 ▶).

 

Source:

http://doi.org/10.1107/S160053681202990X

 

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